Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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92 genes differentially expressed following the BRD-K53561341_KIN001-220_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
CPM | carboxypeptidase M |
CTSZ | cathepsin Z |
CXCL13 | chemokine (C-X-C motif) ligand 13 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DDIT4 | DNA-damage-inducible transcript 4 |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
EPAS1 | endothelial PAS domain protein 1 |
FAM69A | family with sequence similarity 69, member A |
FAS | Fas cell surface death receptor |
FHL1 | four and a half LIM domains 1 |
FLRT2 | fibronectin leucine rich transmembrane protein 2 |
FOSL1 | FOS-like antigen 1 |
G0S2 | G0/G1 switch 2 |
GAGE3 | G antigen 3 |
HIST1H2AC | histone cluster 1, H2ac |
HIST2H2BE | histone cluster 2, H2be |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IGHM | immunoglobulin heavy constant mu |
KCTD5 | potassium channel tetramerization domain containing 5 |
MBNL2 | muscleblind-like splicing regulator 2 |
MVP | major vault protein |
OLFM4 | olfactomedin 4 |
PALLD | palladin, cytoskeletal associated protein |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PHF20 | PHD finger protein 20 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PRKCZ | protein kinase C, zeta |
REG1A | regenerating islet-derived 1 alpha |
RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
SERTAD2 | SERTA domain containing 2 |
SOX9 | SRY (sex determining region Y)-box 9 |
STXBP1 | syntaxin binding protein 1 |
TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
TP53I3 | tumor protein p53 inducible protein 3 |
TRIM2 | tripartite motif containing 2 |
TXNIP | thioredoxin interacting protein |
UBB | ubiquitin B |
XIST | X inactive specific transcript (non-protein coding) |
YBX3 | Y box binding protein 3 |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
ZBTB18 | zinc finger and BTB domain containing 18 |
ZMAT3 | zinc finger, matrin-type 3 |
Symbol | Name |
---|---|
ALDOA | aldolase A, fructose-bisphosphate |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BCHE | butyrylcholinesterase |
BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
C3 | complement component 3 |
CCNF | cyclin F |
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
CDK1 | cyclin-dependent kinase 1 |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CHEK2 | checkpoint kinase 2 |
COPS7A | COP9 signalosome subunit 7A |
FAM129A | family with sequence similarity 129, member A |
FGA | fibrinogen alpha chain |
FGB | fibrinogen beta chain |
FGFR2 | fibroblast growth factor receptor 2 |
FGG | fibrinogen gamma chain |
FMOD | fibromodulin |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GINS1 | GINS complex subunit 1 (Psf1 homolog) |
GPC3 | glypican 3 |
HIST1H4C | histone cluster 1, H4c |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
IGFBP4 | insulin-like growth factor binding protein 4 |
KRT19 | keratin 19, type I |
KRT7 | keratin 7, type II |
LXN | latexin |
NREP | neuronal regeneration related protein |
PAH | phenylalanine hydroxylase |
PDE4B | phosphodiesterase 4B, cAMP-specific |
PDGFRL | platelet-derived growth factor receptor-like |
PITX1 | paired-like homeodomain 1 |
PLAT | plasminogen activator, tissue |
PLK1 | polo-like kinase 1 |
POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
PON3 | paraoxonase 3 |
POSTN | periostin, osteoblast specific factor |
RFC5 | replication factor C (activator 1) 5, 36.5kDa |
S100A6 | S100 calcium binding protein A6 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
UBE2C | ubiquitin-conjugating enzyme E2C |
UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |