Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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61 genes differentially expressed following the BRD-K53566850_1-(4-chlorobenzyl)-4-[4-(2-methylphenyl)-1-piperazinyl]-1H-pyrazolo[3,4-d]pyrimidine_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACAA2 | acetyl-CoA acyltransferase 2 |
ANGPTL2 | angiopoietin-like 2 |
ATF3 | activating transcription factor 3 |
BZW2 | basic leucine zipper and W2 domains 2 |
CASP7 | caspase 7, apoptosis-related cysteine peptidase |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
COL11A1 | collagen, type XI, alpha 1 |
COL5A1 | collagen, type V, alpha 1 |
COMP | cartilage oligomeric matrix protein |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
GAS1 | growth arrest-specific 1 |
GATA6 | GATA binding protein 6 |
GSTM3 | glutathione S-transferase mu 3 (brain) |
IGFBP5 | insulin-like growth factor binding protein 5 |
IGL | immunoglobulin lambda locus |
INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
KLF2 | Kruppel-like factor 2 |
LMCD1 | LIM and cysteine-rich domains 1 |
MAMLD1 | mastermind-like domain containing 1 |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
NMU | neuromedin U |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PDLIM3 | PDZ and LIM domain 3 |
PEG10 | paternally expressed 10 |
PLAT | plasminogen activator, tissue |
PLCB4 | phospholipase C, beta 4 |
POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa |
RGS2 | regulator of G-protein signaling 2 |
RRAGD | Ras-related GTP binding D |
S100A14 | S100 calcium binding protein A14 |
SCYL3 | SCY1-like 3 (S. cerevisiae) |
SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
SOX9 | SRY (sex determining region Y)-box 9 |
TESK1 | testis-specific kinase 1 |
THBS1 | thrombospondin 1 |
TUBA1A | tubulin, alpha 1a |
Symbol | Name |
---|---|
ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
C2CD2 | C2 calcium-dependent domain containing 2 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DCLK1 | doublecortin-like kinase 1 |
GAL | galanin/GMAP prepropeptide |
GOLGA8A | golgin A8 family, member A |
GOLGA8B | golgin A8 family, member B |
KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
MX1 | MX dynamin-like GTPase 1 |
NEFH | neurofilament, heavy polypeptide |
NEFL | neurofilament, light polypeptide |
P3H2 | prolyl 3-hydroxylase 2 |
PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
RNASET2 | ribonuclease T2 |
RPL38 | ribosomal protein L38 |
RUNX3 | runt-related transcription factor 3 |
SEPP1 | selenoprotein P, plasma, 1 |
SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
SYBU | syntabulin (syntaxin-interacting) |
TBX3 | T-box 3 |
TGFBI | transforming growth factor, beta-induced, 68kDa |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
ZNF589 | zinc finger protein 589 |