BRD-K53972329_ruxolitinib_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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39 genes differentially expressed following the BRD-K53972329_ruxolitinib_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CLEC11A C-type lectin domain family 11, member A
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
GANAB glucosidase, alpha; neutral AB
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGHD immunoglobulin heavy constant delta
IGKV4-1 immunoglobulin kappa variable 4-1
LMO4 LIM domain only 4
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TBX2 T-box 2
WT1 Wilms tumor 1

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADRB2 adrenoceptor beta 2, surface
CDKN2A cyclin-dependent kinase inhibitor 2A
CRYAB crystallin, alpha B
DLK1 delta-like 1 homolog (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EDN1 endothelin 1
EMP1 epithelial membrane protein 1
FRZB frizzled-related protein
GJA1 gap junction protein, alpha 1, 43kDa
JUND jun D proto-oncogene
LEPR leptin receptor
NPTX2 neuronal pentraxin II
RBP1 retinol binding protein 1, cellular
RGS5 regulator of G-protein signaling 5
RPS11 ribosomal protein S11
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH3YL1 SH3 and SYLF domain containing 1
STMN2 stathmin 2
STOM stomatin
TCF4 transcription factor 4
THBD thrombomodulin
TM4SF1 transmembrane 4 L six family member 1
TPMT thiopurine S-methyltransferase
TWIST1 twist family bHLH transcription factor 1
ZNF423 zinc finger protein 423