| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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60 genes differentially expressed following the BRD-K53972329_ruxolitinib_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACKR3 | atypical chemokine receptor 3 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AREG | amphiregulin |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CPE | carboxypeptidase E |
| CRTAP | cartilage associated protein |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPX3 | glutathione peroxidase 3 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IGHM | immunoglobulin heavy constant mu |
| KIAA0101 | KIAA0101 |
| KLHDC10 | kelch domain containing 10 |
| PSAP | prosaposin |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TSC22D1 | TSC22 domain family, member 1 |
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADD3 | adducin 3 (gamma) |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| CLDN10 | claudin 10 |
| COCH | cochlin |
| COL1A1 | collagen, type I, alpha 1 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAS | Fas cell surface death receptor |
| FGFR3 | fibroblast growth factor receptor 3 |
| FOLR1 | folate receptor 1 (adult) |
| GLDC | glycine dehydrogenase (decarboxylating) |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| PHACTR1 | phosphatase and actin regulator 1 |
| PPARG | peroxisome proliferator-activated receptor gamma |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| RGS4 | regulator of G-protein signaling 4 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SNAI2 | snail family zinc finger 2 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| STC2 | stanniocalcin 2 |
| TPM1 | tropomyosin 1 (alpha) |
| TSPAN8 | tetraspanin 8 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
