Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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112 genes differentially expressed following the BRD-K54606188_(+)-JQ1_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ASMTL | acetylserotonin O-methyltransferase-like |
BLNK | B-cell linker |
BTG1 | B-cell translocation gene 1, anti-proliferative |
BTG2 | BTG family, member 2 |
CADM1 | cell adhesion molecule 1 |
CD52 | CD52 molecule |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
CLCA1 | chloride channel accessory 1 |
COL13A1 | collagen, type XIII, alpha 1 |
CPA3 | carboxypeptidase A3 (mast cell) |
CXADR | coxsackie virus and adenovirus receptor |
EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
EZR | ezrin |
FOLR1 | folate receptor 1 (adult) |
H2BFS | H2B histone family, member S (pseudogene) |
HEBP1 | heme binding protein 1 |
HIST1H1C | histone cluster 1, H1c |
HIST1H2BD | histone cluster 1, H2bd |
HIST1H2BK | histone cluster 1, H2bk |
HOXA5 | homeobox A5 |
IGHD | immunoglobulin heavy constant delta |
JUN | jun proto-oncogene |
KIF2C | kinesin family member 2C |
KLF4 | Kruppel-like factor 4 (gut) |
LTBP1 | latent transforming growth factor beta binding protein 1 |
MAN2A1 | mannosidase, alpha, class 2A, member 1 |
MEF2C | myocyte enhancer factor 2C |
METTL7A | methyltransferase like 7A |
MUC2 | mucin 2, oligomeric mucus/gel-forming |
NBPF10 | neuroblastoma breakpoint family, member 10 |
NID2 | nidogen 2 (osteonidogen) |
NTS | neurotensin |
PAX5 | paired box 5 |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PSIP1 | PC4 and SFRS1 interacting protein 1 |
REG1A | regenerating islet-derived 1 alpha |
RGS2 | regulator of G-protein signaling 2 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SEPP1 | selenoprotein P, plasma, 1 |
SKAP2 | src kinase associated phosphoprotein 2 |
SPON1 | spondin 1, extracellular matrix protein |
TOX3 | TOX high mobility group box family member 3 |
TXNIP | thioredoxin interacting protein |
VNN1 | vanin 1 |
ZNF131 | zinc finger protein 131 |
Symbol | Name |
---|---|
ADGRE5 | adhesion G protein-coupled receptor E5 |
ALCAM | activated leukocyte cell adhesion molecule |
ANXA3 | annexin A3 |
APOD | apolipoprotein D |
AQP3 | aquaporin 3 (Gill blood group) |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
CBR3 | carbonyl reductase 3 |
CCL2 | chemokine (C-C motif) ligand 2 |
CD44 | CD44 molecule (Indian blood group) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CHI3L2 | chitinase 3-like 2 |
CST1 | cystatin SN |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL11 | chemokine (C-X-C motif) ligand 11 |
CXCL5 | chemokine (C-X-C motif) ligand 5 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
CYTH1 | cytohesin 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DOCK10 | dedicator of cytokinesis 10 |
EDN1 | endothelin 1 |
EGF | epidermal growth factor |
FABP7 | fatty acid binding protein 7, brain |
FAM129A | family with sequence similarity 129, member A |
FOSL1 | FOS-like antigen 1 |
GBP1 | guanylate binding protein 1, interferon-inducible |
GBP2 | guanylate binding protein 2, interferon-inducible |
GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
ICAM1 | intercellular adhesion molecule 1 |
IFRD2 | interferon-related developmental regulator 2 |
IGFBP3 | insulin-like growth factor binding protein 3 |
IL32 | interleukin 32 |
ISG20 | interferon stimulated exonuclease gene 20kDa |
JMJD6 | jumonji domain containing 6 |
KRT17 | keratin 17, type I |
KRT6B | keratin 6B, type II |
LIMCH1 | LIM and calponin homology domains 1 |
LOX | lysyl oxidase |
MAPK13 | mitogen-activated protein kinase 13 |
MYBPC1 | myosin binding protein C, slow type |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
NMB | neuromedin B |
PDLIM5 | PDZ and LIM domain 5 |
PLCB4 | phospholipase C, beta 4 |
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
PYCR1 | pyrroline-5-carboxylate reductase 1 |
S100B | S100 calcium binding protein B |
SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
SLPI | secretory leukocyte peptidase inhibitor |
SORBS2 | sorbin and SH3 domain containing 2 |
SORBS3 | sorbin and SH3 domain containing 3 |
SOX9 | SRY (sex determining region Y)-box 9 |
SRPX2 | sushi-repeat containing protein, X-linked 2 |
STC2 | stanniocalcin 2 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TARP | TCR gamma alternate reading frame protein |
TM4SF1 | transmembrane 4 L six family member 1 |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
XBP1 | X-box binding protein 1 |
YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 |