| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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119 genes differentially expressed following the BRD-K54606188_(+)-JQ1_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BZW2 | basic leucine zipper and W2 domains 2 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CAV2 | caveolin 2 |
| CCDC92 | coiled-coil domain containing 92 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD44 | CD44 molecule (Indian blood group) |
| CLEC3B | C-type lectin domain family 3, member B |
| CLIC3 | chloride intracellular channel 3 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP6 | dual specificity phosphatase 6 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFNB2 | ephrin-B2 |
| EGR1 | early growth response 1 |
| EZR | ezrin |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FERMT2 | fermitin family member 2 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FHL1 | four and a half LIM domains 1 |
| FSTL1 | follistatin-like 1 |
| G0S2 | G0/G1 switch 2 |
| GPM6B | glycoprotein M6B |
| GRB14 | growth factor receptor-bound protein 14 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| KIF2C | kinesin family member 2C |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| NMT2 | N-myristoyltransferase 2 |
| NOTCH2NL | notch 2 N-terminal like |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| QKI | QKI, KH domain containing, RNA binding |
| RND3 | Rho family GTPase 3 |
| SCAF4 | SR-related CTD-associated factor 4 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SMAD7 | SMAD family member 7 |
| STC2 | stanniocalcin 2 |
| TAGLN | transgelin |
| TCF4 | transcription factor 4 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM50A | transmembrane protein 50A |
| TOX3 | TOX high mobility group box family member 3 |
| TSPAN13 | tetraspanin 13 |
| TSPAN3 | tetraspanin 3 |
| TUBA1A | tubulin, alpha 1a |
| ZNF274 | zinc finger protein 274 |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ABLIM1 | actin binding LIM protein 1 |
| ANPEP | alanyl (membrane) aminopeptidase |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APOL3 | apolipoprotein L, 3 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BCHE | butyrylcholinesterase |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CA12 | carbonic anhydrase XII |
| CD200 | CD200 molecule |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CLEC5A | C-type lectin domain family 5, member A |
| COL1A1 | collagen, type I, alpha 1 |
| COL6A2 | collagen, type VI, alpha 2 |
| CYTIP | cytohesin 1 interacting protein |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| ICAM3 | intercellular adhesion molecule 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| IL17RB | interleukin 17 receptor B |
| IL1R2 | interleukin 1 receptor, type II |
| KIZ | kizuna centrosomal protein |
| KRT18 | keratin 18, type I |
| MAMLD1 | mastermind-like domain containing 1 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MMP9 | matrix metallopeptidase 9 |
| MSLN | mesothelin |
| NKX3-1 | NK3 homeobox 1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PLAC8 | placenta-specific 8 |
| PRKCA | protein kinase C, alpha |
| PRR5 | proline rich 5 (renal) |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RAP1GAP | RAP1 GTPase activating protein |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPP1 | secreted phosphoprotein 1 |
| SPRR3 | small proline-rich protein 3 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| ST5 | suppression of tumorigenicity 5 |
| TARP | TCR gamma alternate reading frame protein |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TXNIP | thioredoxin interacting protein |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WT1 | Wilms tumor 1 |
