| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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189 genes differentially expressed following the BRD-K54606188_(+)-JQ1_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| BGN | biglycan |
| CA2 | carbonic anhydrase II |
| CCDC85B | coiled-coil domain containing 85B |
| CCDC92 | coiled-coil domain containing 92 |
| CD24 | CD24 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CIRBP | cold inducible RNA binding protein |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CREG1 | cellular repressor of E1A-stimulated genes 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CTSK | cathepsin K |
| DLX2 | distal-less homeobox 2 |
| DMXL2 | Dmx-like 2 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DUSP22 | dual specificity phosphatase 22 |
| DUSP6 | dual specificity phosphatase 6 |
| FERMT2 | fermitin family member 2 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GPM6B | glycoprotein M6B |
| GPR137B | G protein-coupled receptor 137B |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| H2BFS | H2B histone family, member S (pseudogene) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H2BK | histone cluster 1, H2bk |
| HIST1H3H | histone cluster 1, H3h |
| HIST2H2BE | histone cluster 2, H2be |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGKC | immunoglobulin kappa constant |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| INPP5F | inositol polyphosphate-5-phosphatase F |
| ITGA6 | integrin, alpha 6 |
| KLF10 | Kruppel-like factor 10 |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LPIN1 | lipin 1 |
| LRRC15 | leucine rich repeat containing 15 |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MAP1A | microtubule-associated protein 1A |
| MFAP3L | microfibrillar-associated protein 3-like |
| MMP1 | matrix metallopeptidase 1 |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NEFL | neurofilament, light polypeptide |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| ODC1 | ornithine decarboxylase 1 |
| PALLD | palladin, cytoskeletal associated protein |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PDZD8 | PDZ domain containing 8 |
| PEG3 | paternally expressed 3 |
| PLK2 | polo-like kinase 2 |
| PNKP | polynucleotide kinase 3'-phosphatase |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RHOB | ras homolog family member B |
| RRAGD | Ras-related GTP binding D |
| RUFY3 | RUN and FYVE domain containing 3 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEPT10 | septin 10 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SF1 | splicing factor 1 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| SST | somatostatin |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| STOM | stomatin |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
| STXBP1 | syntaxin binding protein 1 |
| TPD52L1 | tumor protein D52-like 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TSC22D2 | TSC22 domain family, member 2 |
| TSPYL5 | TSPY-like 5 |
| VCL | vinculin |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACP2 | acid phosphatase 2, lysosomal |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APOC2 | apolipoprotein C-II |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| C3 | complement component 3 |
| CA1 | carbonic anhydrase I |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CCDC86 | coiled-coil domain containing 86 |
| CD58 | CD58 molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFI | complement factor I |
| CLCA4 | chloride channel accessory 4 |
| COL4A2 | collagen, type IV, alpha 2 |
| CPM | carboxypeptidase M |
| CSTA | cystatin A (stefin A) |
| CTSH | cathepsin H |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| EMP1 | epithelial membrane protein 1 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| FAM129A | family with sequence similarity 129, member A |
| GOLT1B | golgi transport 1B |
| GPR171 | G protein-coupled receptor 171 |
| GYPC | glycophorin C (Gerbich blood group) |
| HMGA2 | high mobility group AT-hook 2 |
| HNMT | histamine N-methyltransferase |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPB1 | heat shock 27kDa protein 1 |
| ICAM3 | intercellular adhesion molecule 3 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL1B | interleukin 1, beta |
| IL1R2 | interleukin 1 receptor, type II |
| IL1RN | interleukin 1 receptor antagonist |
| IL27RA | interleukin 27 receptor, alpha |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| JADE2 | jade family PHD finger 2 |
| KRT14 | keratin 14, type I |
| KRT15 | keratin 15, type I |
| KRT17 | keratin 17, type I |
| KRT18 | keratin 18, type I |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LIPA | lipase A, lysosomal acid, cholesterol esterase |
| LMNB1 | lamin B1 |
| LOX | lysyl oxidase |
| LPL | lipoprotein lipase |
| MAL | mal, T-cell differentiation protein |
| MANSC1 | MANSC domain containing 1 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MGST2 | microsomal glutathione S-transferase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MPZL2 | myelin protein zero-like 2 |
| NMI | N-myc (and STAT) interactor |
| NRIP1 | nuclear receptor interacting protein 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B |
| PIP | prolactin-induced protein |
| POSTN | periostin, osteoblast specific factor |
| PPL | periplakin |
| PRKCD | protein kinase C, delta |
| PRKCH | protein kinase C, eta |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RCC1 | regulator of chromosome condensation 1 |
| RPS11 | ribosomal protein S11 |
| S100A2 | S100 calcium binding protein A2 |
| S100A4 | S100 calcium binding protein A4 |
| S100A6 | S100 calcium binding protein A6 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCEL | sciellin |
| SEPT9 | septin 9 |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TF | transferrin |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TRIM2 | tripartite motif containing 2 |
| TSPAN4 | tetraspanin 4 |
| VCAN | versican |
