Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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63 genes differentially expressed following the BRD-K54997624_BYL719_MCF10A_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACSL1 | acyl-CoA synthetase long-chain family member 1 |
ADGRG6 | adhesion G protein-coupled receptor G6 |
APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
BTG1 | B-cell translocation gene 1, anti-proliferative |
CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CHIC2 | cysteine-rich hydrophobic domain 2 |
CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DPYSL2 | dihydropyrimidinase-like 2 |
DUSP1 | dual specificity phosphatase 1 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
GRK5 | G protein-coupled receptor kinase 5 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
KDM5D | lysine (K)-specific demethylase 5D |
KYNU | kynureninase |
MAOA | monoamine oxidase A |
NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
PHKB | phosphorylase kinase, beta |
PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TSC22D3 | TSC22 domain family, member 3 |
USP6NL | USP6 N-terminal like |
Symbol | Name |
---|---|
ACTR2 | ARP2 actin-related protein 2 homolog (yeast) |
ADM | adrenomedullin |
ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
BEX1 | brain expressed, X-linked 1 |
BHLHE41 | basic helix-loop-helix family, member e41 |
C3 | complement component 3 |
CBFB | core-binding factor, beta subunit |
CCND1 | cyclin D1 |
COL5A2 | collagen, type V, alpha 2 |
CPVL | carboxypeptidase, vitellogenic-like |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
EGR2 | early growth response 2 |
EPHA3 | EPH receptor A3 |
JUN | jun proto-oncogene |
KRT17 | keratin 17, type I |
LMO3 | LIM domain only 3 (rhombotin-like 2) |
NOSIP | nitric oxide synthase interacting protein |
PLBD1 | phospholipase B domain containing 1 |
PPIF | peptidylprolyl isomerase F |
PRMT1 | protein arginine methyltransferase 1 |
RPIA | ribose 5-phosphate isomerase A |
SDC4 | syndecan 4 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SFN | stratifin |
SOX9 | SRY (sex determining region Y)-box 9 |
SPAG4 | sperm associated antigen 4 |
TF | transferrin |
TNC | tenascin C |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
TUBB2A | tubulin, beta 2A class IIa |