| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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108 genes differentially expressed following the BRD-K54997624_BYL719_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| AHR | aryl hydrocarbon receptor |
| AIM1 | absent in melanoma 1 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APOD | apolipoprotein D |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCDC92 | coiled-coil domain containing 92 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CES1 | carboxylesterase 1 |
| CFB | complement factor B |
| CFD | complement factor D (adipsin) |
| COPA | coatomer protein complex, subunit alpha |
| CPD | carboxypeptidase D |
| CSTA | cystatin A (stefin A) |
| DAPK1 | death-associated protein kinase 1 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DPYSL3 | dihydropyrimidinase-like 3 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| EGFL6 | EGF-like-domain, multiple 6 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GAS1 | growth arrest-specific 1 |
| GDF15 | growth differentiation factor 15 |
| GHR | growth hormone receptor |
| GPATCH8 | G patch domain containing 8 |
| GRN | granulin |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| HNMT | histamine N-methyltransferase |
| IFITM1 | interferon induced transmembrane protein 1 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 |
| IRS2 | insulin receptor substrate 2 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLHDC10 | kelch domain containing 10 |
| LCN2 | lipocalin 2 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LIMK2 | LIM domain kinase 2 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MDFIC | MyoD family inhibitor domain containing |
| MEIS1 | Meis homeobox 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MTMR11 | myotubularin related protein 11 |
| S100P | S100 calcium binding protein P |
| SECISBP2L | SECIS binding protein 2-like |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| STC2 | stanniocalcin 2 |
| SULF1 | sulfatase 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TRIM22 | tripartite motif containing 22 |
| TSC22D1 | TSC22 domain family, member 1 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| ZNF423 | zinc finger protein 423 |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AK1 | adenylate kinase 1 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa |
| AURKA | aurora kinase A |
| BIRC5 | baculoviral IAP repeat containing 5 |
| CALCA | calcitonin-related polypeptide alpha |
| CCNA2 | cyclin A2 |
| CD24 | CD24 molecule |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CKB | creatine kinase, brain |
| CRYAB | crystallin, alpha B |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| EBP | emopamil binding protein (sterol isomerase) |
| EGFR | epidermal growth factor receptor |
| EPCAM | epithelial cell adhesion molecule |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FABP7 | fatty acid binding protein 7, brain |
| GLIPR1 | GLI pathogenesis-related 1 |
| GUSBP11 | glucuronidase, beta pseudogene 11 |
| HN1 | hematological and neurological expressed 1 |
| HOXC10 | homeobox C10 |
| HSPA1A | heat shock 70kDa protein 1A |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGHD | immunoglobulin heavy constant delta |
| IGKC | immunoglobulin kappa constant |
| IGL | immunoglobulin lambda locus |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| KIF20A | kinesin family member 20A |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| KRT14 | keratin 14, type I |
| KRT16 | keratin 16, type I |
| KRT6A | keratin 6A, type II |
| LRRC17 | leucine rich repeat containing 17 |
| MAGEA12 | melanoma antigen family A12 |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| NEK2 | NIMA-related kinase 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| PKN2 | protein kinase N2 |
| PLK1 | polo-like kinase 1 |
| RBP1 | retinol binding protein 1, cellular |
| S100A2 | S100 calcium binding protein A2 |
| SET | SET nuclear proto-oncogene |
| SLPI | secretory leukocyte peptidase inhibitor |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TUBB4B | tubulin, beta 4B class IVb |
| UBE2S | ubiquitin-conjugating enzyme E2S |
