BRD-K54997624_BYL719_SKBR3_3_h_3.33_um Gene Set
Genes
61 genes differentially expressed following the BRD-K54997624_BYL719_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
|
C6ORF62
|
chromosome 6 open reading frame 62
|
|
CD46
|
CD46 molecule, complement regulatory protein
|
|
CD52
|
CD52 molecule
|
|
CHN1
|
chimerin 1
|
|
CPS1
|
carbamoyl-phosphate synthase 1, mitochondrial
|
|
CST6
|
cystatin E/M
|
|
CYP1B1
|
cytochrome P450, family 1, subfamily B, polypeptide 1
|
|
DSC1
|
desmocollin 1
|
|
DSP
|
desmoplakin
|
|
FGFR3
|
fibroblast growth factor receptor 3
|
|
GNG11
|
guanine nucleotide binding protein (G protein), gamma 11
|
|
GPNMB
|
glycoprotein (transmembrane) nmb
|
|
HIST1H1C
|
histone cluster 1, H1c
|
|
IDE
|
insulin-degrading enzyme
|
|
ITGAV
|
integrin, alpha V
|
|
KAT6B
|
K(lysine) acetyltransferase 6B
|
|
LRRC17
|
leucine rich repeat containing 17
|
|
LUM
|
lumican
|
|
NELL2
|
NEL-like 2 (chicken)
|
|
PTGES
|
prostaglandin E synthase
|
|
QPCT
|
glutaminyl-peptide cyclotransferase
|
|
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
|
|
RASGRP1
|
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
|
|
S100A7
|
S100 calcium binding protein A7
|
|
SST
|
somatostatin
|
|
TFAP2A
|
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
|
|
TFAP2B
|
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
|
|
TFPI
|
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
|
|
TRBC1
|
T cell receptor beta constant 1
|
|
TSC22D1
|
TSC22 domain family, member 1
|
|
ZNF217
|
zinc finger protein 217
|
decreased expression
| Symbol |
Name |
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
|
ANXA2P2
|
annexin A2 pseudogene 2
|
|
ANXA3
|
annexin A3
|
|
BID
|
BH3 interacting domain death agonist
|
|
C1QA
|
complement component 1, q subcomponent, A chain
|
|
CD24
|
CD24 molecule
|
|
CEACAM5
|
carcinoembryonic antigen-related cell adhesion molecule 5
|
|
CHGB
|
chromogranin B
|
|
CYP4B1
|
cytochrome P450, family 4, subfamily B, polypeptide 1
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
|
FGF9
|
fibroblast growth factor 9
|
|
HOXB2
|
homeobox B2
|
|
IGFBP4
|
insulin-like growth factor binding protein 4
|
|
KRT23
|
keratin 23, type I
|
|
KRT8
|
keratin 8, type II
|
|
MGLL
|
monoglyceride lipase
|
|
PHLDA1
|
pleckstrin homology-like domain, family A, member 1
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
|
RBP1
|
retinol binding protein 1, cellular
|
|
RGCC
|
regulator of cell cycle
|
|
RNH1
|
ribonuclease/angiogenin inhibitor 1
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
|
SERPINE2
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
|
|
SIX2
|
SIX homeobox 2
|
|
SLC2A5
|
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
|
|
SOX11
|
SRY (sex determining region Y)-box 11
|
|
TUBA4A
|
tubulin, alpha 4a
|
