| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
144 genes differentially expressed following the BRD-K55187425_ON-01910_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AAK1 | AP2 associated kinase 1 |
| ABHD2 | abhydrolase domain containing 2 |
| ACOT9 | acyl-CoA thioesterase 9 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ANKRD11 | ankyrin repeat domain 11 |
| ANXA3 | annexin A3 |
| ARHGAP6 | Rho GTPase activating protein 6 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BAG2 | BCL2-associated athanogene 2 |
| BPTF | bromodomain PHD finger transcription factor |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CD9 | CD9 molecule |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLEC2B | C-type lectin domain family 2, member B |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM129A | family with sequence similarity 129, member A |
| FAM46A | family with sequence similarity 46, member A |
| FHL2 | four and a half LIM domains 2 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOSL1 | FOS-like antigen 1 |
| G0S2 | G0/G1 switch 2 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GRB10 | growth factor receptor-bound protein 10 |
| GSN | gelsolin |
| IFRD1 | interferon-related developmental regulator 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGAV | integrin, alpha V |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LRP10 | low density lipoprotein receptor-related protein 10 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MARCKSL1 | MARCKS-like 1 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MEIS1 | Meis homeobox 1 |
| MICALL1 | MICAL-like 1 |
| MT1E | metallothionein 1E |
| MTCL1 | microtubule crosslinking factor 1 |
| MVP | major vault protein |
| MXRA7 | matrix-remodelling associated 7 |
| OSBPL3 | oxysterol binding protein-like 3 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PFKP | phosphofructokinase, platelet |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PODXL | podocalyxin-like |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| S100A11 | S100 calcium binding protein A11 |
| S100A2 | S100 calcium binding protein A2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SMTN | smoothelin |
| SNAI2 | snail family zinc finger 2 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SP100 | SP100 nuclear antigen |
| SP110 | SP110 nuclear body protein |
| SRPX | sushi-repeat containing protein, X-linked |
| SRRM2 | serine/arginine repetitive matrix 2 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 |
| TOMM34 | translocase of outer mitochondrial membrane 34 |
| TPM4 | tropomyosin 4 |
| TUBA4A | tubulin, alpha 4a |
| VAMP8 | vesicle-associated membrane protein 8 |
| VNN1 | vanin 1 |
| WSB2 | WD repeat and SOCS box containing 2 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) |
| B3GNT1 | |
| BEX1 | brain expressed, X-linked 1 |
| C5 | complement component 5 |
| CA1 | carbonic anhydrase I |
| CANX | calnexin |
| CD200 | CD200 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDK1 | cyclin-dependent kinase 1 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHMP4A | charged multivesicular body protein 4A |
| CHN2 | chimerin 2 |
| CLU | clusterin |
| CRIP2 | cysteine-rich protein 2 |
| EIF5A | eukaryotic translation initiation factor 5A |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FMO5 | flavin containing monooxygenase 5 |
| FST | follistatin |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPC3 | glypican 3 |
| HBB | hemoglobin, beta |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGA2 | high mobility group AT-hook 2 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| JAM3 | junctional adhesion molecule 3 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LTF | lactotransferrin |
| MAOB | monoamine oxidase B |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
| MELK | maternal embryonic leucine zipper kinase |
| MSH2 | mutS homolog 2 |
| MSH6 | mutS homolog 6 |
| MSMB | microseminoprotein, beta- |
| MSMO1 | methylsterol monooxygenase 1 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| PAH | phenylalanine hydroxylase |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDIA6 | protein disulfide isomerase family A, member 6 |
| PGM1 | phosphoglucomutase 1 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RRM2 | ribonucleotide reductase M2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPP1 | secreted phosphoprotein 1 |
| TF | transferrin |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM97 | transmembrane protein 97 |
| TMPO | thymopoietin |
| TNS3 | tensin 3 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| XBP1 | X-box binding protein 1 |
