BRD-K55468218_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K55468218_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASS1 argininosuccinate synthase 1
CCNG2 cyclin G2
CD99 CD99 molecule
COL1A2 collagen, type I, alpha 2
CYB5A cytochrome b5 type A (microsomal)
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FKBP11 FK506 binding protein 11, 19 kDa
GDF15 growth differentiation factor 15
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX glutaredoxin (thioltransferase)
INSIG1 insulin induced gene 1
LAMP2 lysosomal-associated membrane protein 2
MBNL2 muscleblind-like splicing regulator 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MME membrane metallo-endopeptidase
NAMPT nicotinamide phosphoribosyltransferase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NNMT nicotinamide N-methyltransferase
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUCB2 nucleobindin 2
PDGFRL platelet-derived growth factor receptor-like
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RBM47 RNA binding motif protein 47
RPS4Y1 ribosomal protein S4, Y-linked 1
SEC24D SEC24 family member D
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC35B1 solute carrier family 35, member B1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTSSA serine palmitoyltransferase, small subunit A
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
BEX1 brain expressed, X-linked 1
CA2 carbonic anhydrase II
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
MGLL monoglyceride lipase
PRKCA protein kinase C, alpha
SATB2 SATB homeobox 2
Funding