BRD-K55827386_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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41 genes differentially expressed following the BRD-K55827386_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AHCYL1 adenosylhomocysteinase-like 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BTG1 B-cell translocation gene 1, anti-proliferative
CD36 CD36 molecule (thrombospondin receptor)
CDKN2A cyclin-dependent kinase inhibitor 2A
COL3A1 collagen, type III, alpha 1
COLEC12 collectin sub-family member 12
CRABP2 cellular retinoic acid binding protein 2
CTSZ cathepsin Z
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEFA5 defensin, alpha 5, Paneth cell-specific
IL13RA1 interleukin 13 receptor, alpha 1
IL1B interleukin 1, beta
LGALS1 lectin, galactoside-binding, soluble, 1
MTSS1 metastasis suppressor 1
PRAME preferentially expressed antigen in melanoma
SIK1 salt-inducible kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX9 SRY (sex determining region Y)-box 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYNM synemin, intermediate filament protein
TUBA1A tubulin, alpha 1a
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AXIN1 axin 1
C7 complement component 7
CIAPIN1 cytokine induced apoptosis inhibitor 1
CKS2 CDC28 protein kinase regulatory subunit 2
CNPY3 canopy FGF signaling regulator 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
GYG1 glycogenin 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PI3 peptidase inhibitor 3, skin-derived
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SFRP1 secreted frizzled-related protein 1
SLPI secretory leukocyte peptidase inhibitor
TAGLN transgelin
TJP2 tight junction protein 2
VCAM1 vascular cell adhesion molecule 1