BRD-K55844427_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K55844427_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ADIRF adipogenesis regulatory factor
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ATF3 activating transcription factor 3
BID BH3 interacting domain death agonist
BTG2 BTG family, member 2
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
CA4 carbonic anhydrase IV
COBLL1 cordon-bleu WH2 repeat protein-like 1
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CXADR coxsackie virus and adenovirus receptor
CXCL2 chemokine (C-X-C motif) ligand 2
DCN decorin
EGFL6 EGF-like-domain, multiple 6
EGR1 early growth response 1
EPAS1 endothelial PAS domain protein 1
EXPH5 exophilin 5
FABP4 fatty acid binding protein 4, adipocyte
FBP1 fructose-1,6-bisphosphatase 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR2 fibroblast growth factor receptor 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GPM6B glycoprotein M6B
H2AFV H2A histone family, member V
HBB hemoglobin, beta
HCAR3 hydroxycarboxylic acid receptor 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
LOC100505650 uncharacterized LOC100505650
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MS4A12 membrane-spanning 4-domains, subfamily A, member 12
NEBL nebulette
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM4 olfactomedin 4
ORM1 orosomucoid 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
RAB40B RAB40B, member RAS oncogene family
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
SRGN serglycin
ST18 suppression of tumorigenicity 18, zinc finger
TTC39A tetratricopeptide repeat domain 39A
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VTCN1 V-set domain containing T cell activation inhibitor 1
ZG16 zymogen granule protein 16

decreased expression

Symbol Name
BAG3 BCL2-associated athanogene 3
CRISP3 cysteine-rich secretory protein 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
NPC2 Niemann-Pick disease, type C2
PDGFC platelet derived growth factor C
S100P S100 calcium binding protein P
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
VGLL4 vestigial-like family member 4