| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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81 genes differentially expressed following the BRD-K56343971_HY-10247_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALAD | aminolevulinate dehydratase |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CA2 | carbonic anhydrase II |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CDK19 | cyclin-dependent kinase 19 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLIC4 | chloride intracellular channel 4 |
| DARS | aspartyl-tRNA synthetase |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 |
| DUSP4 | dual specificity phosphatase 4 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| GOLGA8B | golgin A8 family, member B |
| H1FX | H1 histone family, member X |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H3H | histone cluster 1, H3h |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IL6ST | interleukin 6 signal transducer |
| IRX5 | iroquois homeobox 5 |
| KDM3A | lysine (K)-specific demethylase 3A |
| LXN | latexin |
| MAOB | monoamine oxidase B |
| MXI1 | MAX interactor 1, dimerization protein |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NBR1 | neighbor of BRCA1 gene 1 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
| SPATA20 | spermatogenesis associated 20 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SVIL | supervillin |
| TMEM123 | transmembrane protein 123 |
| TPD52 | tumor protein D52 |
| TXNIP | thioredoxin interacting protein |
| VIM | vimentin |
| WSB1 | WD repeat and SOCS box containing 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ATF5 | activating transcription factor 5 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b |
| C14ORF2 | chromosome 14 open reading frame 2 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCND3 | cyclin D3 |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CORO1A | coronin, actin binding protein, 1A |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| EFNB2 | ephrin-B2 |
| FGL2 | fibrinogen-like 2 |
| GALE | UDP-galactose-4-epimerase |
| GLRX2 | glutaredoxin 2 |
| GPNMB | glycoprotein (transmembrane) nmb |
| HBEGF | heparin-binding EGF-like growth factor |
| HDAC9 | histone deacetylase 9 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| INSIG1 | insulin induced gene 1 |
| JMJD6 | jumonji domain containing 6 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MME | membrane metallo-endopeptidase |
| PAK1IP1 | PAK1 interacting protein 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PNP | purine nucleoside phosphorylase |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| SDC2 | syndecan 2 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SPEN | spen family transcriptional repressor |
| STK17A | serine/threonine kinase 17a |
| ZW10 | zw10 kinetochore protein |
