| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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61 genes differentially expressed following the BRD-K56343971_vemurafenib_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ARL4C | ADP-ribosylation factor-like 4C |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CNN3 | calponin 3, acidic |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| EPHA3 | EPH receptor A3 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FGG | fibrinogen gamma chain |
| FOXG1 | forkhead box G1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| LMNA | lamin A/C |
| MAP1B | microtubule-associated protein 1B |
| PEG10 | paternally expressed 10 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTN | pleiotrophin |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RGS4 | regulator of G-protein signaling 4 |
| SFRP1 | secreted frizzled-related protein 1 |
| SPP1 | secreted phosphoprotein 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TPBG | trophoblast glycoprotein |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABLIM1 | actin binding LIM protein 1 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| CALR | calreticulin |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CLDN3 | claudin 3 |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CSTA | cystatin A (stefin A) |
| ECM1 | extracellular matrix protein 1 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| GCH1 | GTP cyclohydrolase 1 |
| H1F0 | H1 histone family, member 0 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IL32 | interleukin 32 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| MAP7 | microtubule-associated protein 7 |
| MEF2C | myocyte enhancer factor 2C |
| MFAP5 | microfibrillar associated protein 5 |
| NCF2 | neutrophil cytosolic factor 2 |
| NGRN | neugrin, neurite outgrowth associated |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDLIM3 | PDZ and LIM domain 3 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| S100A12 | S100 calcium binding protein A12 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SFRP4 | secreted frizzled-related protein 4 |
| STXBP2 | syntaxin binding protein 2 |
| TARP | TCR gamma alternate reading frame protein |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TSPYL5 | TSPY-like 5 |
| VAMP8 | vesicle-associated membrane protein 8 |
| ZBTB16 | zinc finger and BTB domain containing 16 |
