| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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111 genes differentially expressed following the BRD-K56343971_vemurafenib_MCF7_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADD3 | adducin 3 (gamma) |
| ALB | albumin |
| APOE | apolipoprotein E |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| AUTS2 | autism susceptibility candidate 2 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CADM1 | cell adhesion molecule 1 |
| CCND2 | cyclin D2 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLU | clusterin |
| CST1 | cystatin SN |
| CTSB | cathepsin B |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DUSP6 | dual specificity phosphatase 6 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EMX2 | empty spiracles homeobox 2 |
| EPHB2 | EPH receptor B2 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ESRRG | estrogen-related receptor gamma |
| FOXO4 | forkhead box O4 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST3H2A | histone cluster 3, H2a |
| HOXC6 | homeobox C6 |
| HP | haptoglobin |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| KIF5C | kinesin family member 5C |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| PCGF2 | polycomb group ring finger 2 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PEG10 | paternally expressed 10 |
| PLA2G15 | phospholipase A2, group XV |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PLSCR4 | phospholipid scramblase 4 |
| PRAME | preferentially expressed antigen in melanoma |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPON1 | spondin 1, extracellular matrix protein |
| STAT5B | signal transducer and activator of transcription 5B |
| SYT1 | synaptotagmin I |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| VSNL1 | visinin-like 1 |
| Symbol | Name |
|---|---|
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| AIF1 | allograft inflammatory factor 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| CAST | calpastatin |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD200 | CD200 molecule |
| CD24 | CD24 molecule |
| CKLF | chemokine-like factor |
| CREB1 | cAMP responsive element binding protein 1 |
| CRIP2 | cysteine-rich protein 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CSTA | cystatin A (stefin A) |
| CTNND1 | catenin (cadherin-associated protein), delta 1 |
| CTSG | cathepsin G |
| DYNLT3 | dynein, light chain, Tctex-type 3 |
| ECM1 | extracellular matrix protein 1 |
| EFNB2 | ephrin-B2 |
| EPHA3 | EPH receptor A3 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM129A | family with sequence similarity 129, member A |
| FHL1 | four and a half LIM domains 1 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IL1RN | interleukin 1 receptor antagonist |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| KAT6B | K(lysine) acetyltransferase 6B |
| KLF10 | Kruppel-like factor 10 |
| KLF4 | Kruppel-like factor 4 (gut) |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LST1 | leukocyte specific transcript 1 |
| LYZ | lysozyme |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MLPH | melanophilin |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OLFML2A | olfactomedin-like 2A |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PSIP1 | PC4 and SFRS1 interacting protein 1 |
| PXDN | peroxidasin |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RPA3 | replication protein A3, 14kDa |
| S100A6 | S100 calcium binding protein A6 |
| S100A8 | S100 calcium binding protein A8 |
| S100P | S100 calcium binding protein P |
| SLC25A46 | solute carrier family 25, member 46 |
| SOX11 | SRY (sex determining region Y)-box 11 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMSB15A | thymosin beta 15a |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TSPAN13 | tetraspanin 13 |
| TSPAN7 | tetraspanin 7 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) |
| VEGFA | vascular endothelial growth factor A |
