BRD-K56411643_-666_HEC108_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K56411643_-666_HEC108_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADGRL2 adhesion G protein-coupled receptor L2
AKR1C1 aldo-keto reductase family 1, member C1
BAG3 BCL2-associated athanogene 3
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BMP7 bone morphogenetic protein 7
CADM1 cell adhesion molecule 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPYD dihydropyrimidine dehydrogenase
FAM129A family with sequence similarity 129, member A
FOLR1 folate receptor 1 (adult)
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLC glutamate-cysteine ligase, catalytic subunit
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFRD1 interferon-related developmental regulator 1
KLK10 kallikrein-related peptidase 10
LEF1 lymphoid enhancer-binding factor 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LYZ lysozyme
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP7 microtubule-associated protein 7
MMP10 matrix metallopeptidase 10
MZB1 marginal zone B and B1 cell-specific protein
NAMPT nicotinamide phosphoribosyltransferase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NELL2 NEL-like 2 (chicken)
PCP4 Purkinje cell protein 4
PELI1 pellino E3 ubiquitin protein ligase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTN pleiotrophin
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
AP2M1 adaptor-related protein complex 2, mu 1 subunit
APMAP adipocyte plasma membrane associated protein
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
B3GNT1
BACE2 beta-site APP-cleaving enzyme 2
CA12 carbonic anhydrase XII
CCNF cyclin F
CDC20 cell division cycle 20
CLN5 ceroid-lipofuscinosis, neuronal 5
CXCL5 chemokine (C-X-C motif) ligand 5
ERBB2 erb-b2 receptor tyrosine kinase 2
FABP4 fatty acid binding protein 4, adipocyte
FSTL1 follistatin-like 1
FUCA1 fucosidase, alpha-L- 1, tissue
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HIST1H2BK histone cluster 1, H2bk
LAMC1 laminin, gamma 1 (formerly LAMB2)
MAGED1 melanoma antigen family D1
METRN meteorin, glial cell differentiation regulator
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NISCH nischarin
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PEBP1 phosphatidylethanolamine binding protein 1
PLK1 polo-like kinase 1
RPS11 ribosomal protein S11
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TGM2 transglutaminase 2
TNIP1 TNFAIP3 interacting protein 1
UBE2S ubiquitin-conjugating enzyme E2S
VCAM1 vascular cell adhesion molecule 1
Funding