BRD-K56593336_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

48 genes differentially expressed following the BRD-K56593336_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT13 acyl-CoA thioesterase 13
ASNS asparagine synthetase (glutamine-hydrolyzing)
CACYBP calcyclin binding protein
CD52 CD52 molecule
CTSL cathepsin L
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FTH1 ferritin, heavy polypeptide 1
GLUL glutamate-ammonia ligase
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
JCHAIN joining chain of multimeric IgA and IgM
MME membrane metallo-endopeptidase
MT1M metallothionein 1M
NAMPT nicotinamide phosphoribosyltransferase
NEBL nebulette
NEK3 NIMA-related kinase 3
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SQSTM1 sequestosome 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
BCHE butyrylcholinesterase
CCND1 cyclin D1
CHRDL1 chordin-like 1
HLA-F major histocompatibility complex, class I, F
HOXC6 homeobox C6
IER3 immediate early response 3
LAPTM4B lysosomal protein transmembrane 4 beta
MGP matrix Gla protein
NFIB nuclear factor I/B
PNMA2 paraneoplastic Ma antigen 2
QPCT glutaminyl-peptide cyclotransferase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A10 S100 calcium binding protein A10
S100A2 S100 calcium binding protein A2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNC tenascin C
TNS3 tensin 3