| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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118 genes differentially expressed following the BRD-K56593336_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABHD4 | abhydrolase domain containing 4 |
| ACAT1 | acetyl-CoA acetyltransferase 1 |
| ADAM9 | ADAM metallopeptidase domain 9 |
| ADM | adrenomedullin |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| BAG3 | BCL2-associated athanogene 3 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C1QB | complement component 1, q subcomponent, B chain |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IGF1R | insulin-like growth factor 1 receptor |
| IL1R2 | interleukin 1 receptor, type II |
| KAT6B | K(lysine) acetyltransferase 6B |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LDLR | low density lipoprotein receptor |
| LIMCH1 | LIM and calponin homology domains 1 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 |
| MCL1 | myeloid cell leukemia 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| NAMPT | nicotinamide phosphoribosyltransferase |
| NMRK1 | nicotinamide riboside kinase 1 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| RGCC | regulator of cell cycle |
| RIOK3 | RIO kinase 3 |
| RPS21 | ribosomal protein S21 |
| S100A9 | S100 calcium binding protein A9 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFN | stratifin |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SPRR3 | small proline-rich protein 3 |
| STC1 | stanniocalcin 1 |
| SULF1 | sulfatase 1 |
| TTN | titin |
| TXNRD1 | thioredoxin reductase 1 |
| VCAN | versican |
| VEGFA | vascular endothelial growth factor A |
| VNN1 | vanin 1 |
| WT1 | Wilms tumor 1 |
| ZNF395 | zinc finger protein 395 |
| Symbol | Name |
|---|---|
| ACTN1 | actinin, alpha 1 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| ANGPT1 | angiopoietin 1 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
| CLMN | calmin (calponin-like, transmembrane) |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DMD | dystrophin |
| EIF3K | eukaryotic translation initiation factor 3, subunit K |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| FABP7 | fatty acid binding protein 7, brain |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GRB14 | growth factor receptor-bound protein 14 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HOXC6 | homeobox C6 |
| IFI44L | interferon-induced protein 44-like |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| ISG15 | ISG15 ubiquitin-like modifier |
| JADE2 | jade family PHD finger 2 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) |
| LEPR | leptin receptor |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| MAGED1 | melanoma antigen family D1 |
| MDK | midkine (neurite growth-promoting factor 2) |
| MGLL | monoglyceride lipase |
| MID1 | midline 1 |
| MMD | monocyte to macrophage differentiation-associated |
| MMP7 | matrix metallopeptidase 7 |
| MX1 | MX dynamin-like GTPase 1 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa |
| PRAME | preferentially expressed antigen in melanoma |
| RUNX1 | runt-related transcription factor 1 |
| RUNX3 | runt-related transcription factor 3 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| TBCB | tubulin folding cofactor B |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TMEM147 | transmembrane protein 147 |
| TRIM22 | tripartite motif containing 22 |
| TSPYL5 | TSPY-like 5 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF318 | zinc finger protein 318 |
