BRD-K56751279_Y-39983_HS578T_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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89 genes differentially expressed following the BRD-K56751279_Y-39983_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASPH aspartate beta-hydroxylase
CD9 CD9 molecule
CTSH cathepsin H
DNM1 dynamin 1
DTX4 deltex 4, E3 ubiquitin ligase
EMP3 epithelial membrane protein 3
FHL1 four and a half LIM domains 1
G0S2 G0/G1 switch 2
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GPX3 glutathione peroxidase 3
HP haptoglobin
LOX lysyl oxidase
LTF lactotransferrin
MALL mal, T-cell differentiation protein-like
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEF2C myocyte enhancer factor 2C
NFIL3 nuclear factor, interleukin 3 regulated
NQO1 NAD(P)H dehydrogenase, quinone 1
OLFM1 olfactomedin 1
PEX11A peroxisomal biogenesis factor 11 alpha
PFKP phosphofructokinase, platelet
PLAT plasminogen activator, tissue
POSTN periostin, osteoblast specific factor
RGS2 regulator of G-protein signaling 2
RHOBTB3 Rho-related BTB domain containing 3
S100A9 S100 calcium binding protein A9
SDC2 syndecan 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SOX11 SRY (sex determining region Y)-box 11
TGFB1 transforming growth factor, beta 1
TIMP3 TIMP metallopeptidase inhibitor 3
TRIO trio Rho guanine nucleotide exchange factor
ZMYM2 zinc finger, MYM-type 2

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AEBP1 AE binding protein 1
APOD apolipoprotein D
BAMBI BMP and activin membrane-bound inhibitor
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
C10ORF10 chromosome 10 open reading frame 10
CCND2 cyclin D2
CD24 CD24 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DACH1 dachshund family transcription factor 1
EDN1 endothelin 1
EDN3 endothelin 3
EED embryonic ectoderm development
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GADD45B growth arrest and DNA-damage-inducible, beta
GGCT gamma-glutamylcyclotransferase
GIMAP6 GTPase, IMAP family member 6
HAL histidine ammonia-lyase
IER2 immediate early response 2
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
IGF1R insulin-like growth factor 1 receptor
INHBA inhibin, beta A
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
LAMA3 laminin, alpha 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
MT1H metallothionein 1H
MT1X metallothionein 1X
NPIPB3 nuclear pore complex interacting protein family, member B3
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRCAM neuronal cell adhesion molecule
OSR2 odd-skipped related transciption factor 2
PEG10 paternally expressed 10
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPA1 pyrophosphatase (inorganic) 1
SERINC5 serine incorporator 5
SFRP4 secreted frizzled-related protein 4
SNAP25 synaptosomal-associated protein, 25kDa
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
SULF1 sulfatase 1
TFF3 trefoil factor 3 (intestinal)
THBS1 thrombospondin 1
TOB1 transducer of ERBB2, 1
ZFP36L2 ZFP36 ring finger protein-like 2