Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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77 genes differentially expressed following the BRD-K57080016_-666_HA1E_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACTA1 | actin, alpha 1, skeletal muscle |
ADIRF | adipogenesis regulatory factor |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
ANXA1 | annexin A1 |
ARG2 | arginase 2 |
ARID5B | AT rich interactive domain 5B (MRF1-like) |
ATF3 | activating transcription factor 3 |
BAMBI | BMP and activin membrane-bound inhibitor |
C1S | complement component 1, s subcomponent |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
CD58 | CD58 molecule |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CFD | complement factor D (adipsin) |
COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
EGF | epidermal growth factor |
EPAS1 | endothelial PAS domain protein 1 |
FGFR2 | fibroblast growth factor receptor 2 |
FHL1 | four and a half LIM domains 1 |
GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
GPER1 | G protein-coupled estrogen receptor 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IGHM | immunoglobulin heavy constant mu |
LPL | lipoprotein lipase |
MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
NEB | nebulin |
NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
OSR2 | odd-skipped related transciption factor 2 |
PALLD | palladin, cytoskeletal associated protein |
PCSK5 | proprotein convertase subtilisin/kexin type 5 |
PPAP2A | phosphatidic acid phosphatase type 2A |
RCAN1 | regulator of calcineurin 1 |
S100A9 | S100 calcium binding protein A9 |
SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
SPON2 | spondin 2, extracellular matrix protein |
TCF4 | transcription factor 4 |
TGFBR3 | transforming growth factor, beta receptor III |
Symbol | Name |
---|---|
AK2 | adenylate kinase 2 |
CAPG | capping protein (actin filament), gelsolin-like |
CCND1 | cyclin D1 |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
CYTH1 | cytohesin 1 |
DUSP4 | dual specificity phosphatase 4 |
DUSP6 | dual specificity phosphatase 6 |
EIF5A | eukaryotic translation initiation factor 5A |
ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
EXOSC4 | exosome component 4 |
FOSL1 | FOS-like antigen 1 |
GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
GCH1 | GTP cyclohydrolase 1 |
HMGA2 | high mobility group AT-hook 2 |
HOXB2 | homeobox B2 |
IER3 | immediate early response 3 |
IL6ST | interleukin 6 signal transducer |
LIF | leukemia inhibitory factor |
MLPH | melanophilin |
MOK | MOK protein kinase |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NOP16 | NOP16 nucleolar protein |
NT5E | 5'-nucleotidase, ecto (CD73) |
P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PRMT1 | protein arginine methyltransferase 1 |
PTX3 | pentraxin 3, long |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SLC43A3 | solute carrier family 43, member 3 |
SOX9 | SRY (sex determining region Y)-box 9 |
STEAP3 | STEAP family member 3, metalloreductase |
TFPI2 | tissue factor pathway inhibitor 2 |
TM4SF1 | transmembrane 4 L six family member 1 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
VNN1 | vanin 1 |
ZNF91 | zinc finger protein 91 |