| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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171 genes differentially expressed following the BRD-K57080016_-666_RKO_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| A2M | alpha-2-macroglobulin |
| ADAMDEC1 | ADAM-like, decysin 1 |
| ADIRF | adipogenesis regulatory factor |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANPEP | alanyl (membrane) aminopeptidase |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| BEX4 | brain expressed, X-linked 4 |
| BMP4 | bone morphogenetic protein 4 |
| CA2 | carbonic anhydrase II |
| CA4 | carbonic anhydrase IV |
| CCL11 | chemokine (C-C motif) ligand 11 |
| CDC20 | cell division cycle 20 |
| CERS6 | ceramide synthase 6 |
| CES2 | carboxylesterase 2 |
| CHMP4A | charged multivesicular body protein 4A |
| CLC | Charcot-Leyden crystal galectin |
| CNN3 | calponin 3, acidic |
| COL11A1 | collagen, type XI, alpha 1 |
| COLEC12 | collectin sub-family member 12 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CYTIP | cytohesin 1 interacting protein |
| DCN | decorin |
| DENND1B | DENN/MADD domain containing 1B |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| EFHD1 | EF-hand domain family, member D1 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| F11R | F11 receptor |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FHL1 | four and a half LIM domains 1 |
| FOXF1 | forkhead box F1 |
| FOXF2 | forkhead box F2 |
| FUT9 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) |
| GAGE3 | G antigen 3 |
| GATA6 | GATA binding protein 6 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPATCH8 | G patch domain containing 8 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HEPH | hephaestin |
| HIST1H2BG | histone cluster 1, H2bg |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL17RB | interleukin 17 receptor B |
| IL1R1 | interleukin 1 receptor, type I |
| ITGA8 | integrin, alpha 8 |
| KRT19 | keratin 19, type I |
| LAPTM5 | lysosomal protein transmembrane 5 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MMP12 | matrix metallopeptidase 12 |
| MPO | myeloperoxidase |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 |
| NEBL | nebulette |
| NID1 | nidogen 1 |
| ORC1 | origin recognition complex, subunit 1 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCDH7 | protocadherin 7 |
| PCP4 | Purkinje cell protein 4 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| POSTN | periostin, osteoblast specific factor |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| S100A8 | S100 calcium binding protein A8 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SLC38A1 | solute carrier family 38, member 1 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SULF1 | sulfatase 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| THBS1 | thrombospondin 1 |
| TLR4 | toll-like receptor 4 |
| TPR | translocated promoter region, nuclear basket protein |
| TSPAN7 | tetraspanin 7 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| XIST | X inactive specific transcript (non-protein coding) |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| Symbol | Name |
|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
| ANKRD10 | ankyrin repeat domain 10 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CAPNS1 | calpain, small subunit 1 |
| CCDC86 | coiled-coil domain containing 86 |
| CCND1 | cyclin D1 |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DFNA5 | deafness, autosomal dominant 5 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DUSP6 | dual specificity phosphatase 6 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF4A1 | eukaryotic translation initiation factor 4A1 |
| EMP1 | epithelial membrane protein 1 |
| EMP3 | epithelial membrane protein 3 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
| FOLR1 | folate receptor 1 (adult) |
| FOSL1 | FOS-like antigen 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GOLM1 | golgi membrane protein 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HMG20B | high mobility group 20B |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXC6 | homeobox C6 |
| IER3 | immediate early response 3 |
| ITGB1BP1 | integrin beta 1 binding protein 1 |
| ITGB5 | integrin, beta 5 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KLF4 | Kruppel-like factor 4 (gut) |
| LARP4 | La ribonucleoprotein domain family, member 4 |
| LIF | leukemia inhibitory factor |
| LIMA1 | LIM domain and actin binding 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MCL1 | myeloid cell leukemia 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFSD12 | major facilitator superfamily domain containing 12 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NUP88 | nucleoporin 88kDa |
| ODC1 | ornithine decarboxylase 1 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLAUR | plasminogen activator, urokinase receptor |
| PLBD1 | phospholipase B domain containing 1 |
| PLS3 | plastin 3 |
| PNP | purine nucleoside phosphorylase |
| PRMT1 | protein arginine methyltransferase 1 |
| PTGES | prostaglandin E synthase |
| RPL36 | ribosomal protein L36 |
| RPS11 | ribosomal protein S11 |
| RPS21 | ribosomal protein S21 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRP1B | ribosomal RNA processing 1B |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
| STX1A | syntaxin 1A (brain) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| THADA | thyroid adenoma associated |
| TLK2 | tousled-like kinase 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM45A | transmembrane protein 45A |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TSPAN8 | tetraspanin 8 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| UGCG | UDP-glucose ceramide glucosyltransferase |
