| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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50 genes differentially expressed following the BRD-K57080016_selumetinib_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| BZW2 | basic leucine zipper and W2 domains 2 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| FBN1 | fibrillin 1 |
| FBXO21 | F-box protein 21 |
| FN1 | fibronectin 1 |
| GNAS | GNAS complex locus |
| IFT57 | intraflagellar transport 57 |
| INHBA | inhibin, beta A |
| MAOA | monoamine oxidase A |
| MMP7 | matrix metallopeptidase 7 |
| MMP9 | matrix metallopeptidase 9 |
| PROM1 | prominin 1 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| QPCT | glutaminyl-peptide cyclotransferase |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| TESC | tescalcin |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AUTS2 | autism susceptibility candidate 2 |
| CD24 | CD24 molecule |
| CRYAB | crystallin, alpha B |
| DUSP4 | dual specificity phosphatase 4 |
| EFHD1 | EF-hand domain family, member D1 |
| EGR3 | early growth response 3 |
| FAS | Fas cell surface death receptor |
| FOSL1 | FOS-like antigen 1 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IER3 | immediate early response 3 |
| IGHM | immunoglobulin heavy constant mu |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAL | mal, T-cell differentiation protein |
| MBP | myelin basic protein |
| MEF2C | myocyte enhancer factor 2C |
| NAV2 | neuron navigator 2 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SRSF6 | serine/arginine-rich splicing factor 6 |
