| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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65 genes differentially expressed following the BRD-K57080016_selumetinib_MDAMB231_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABLIM1 | actin binding LIM protein 1 |
| ACKR3 | atypical chemokine receptor 3 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CLGN | calmegin |
| CYB5A | cytochrome b5 type A (microsomal) |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EPAS1 | endothelial PAS domain protein 1 |
| FHL1 | four and a half LIM domains 1 |
| FILIP1L | filamin A interacting protein 1-like |
| KLK6 | kallikrein-related peptidase 6 |
| MAL | mal, T-cell differentiation protein |
| MID1IP1 | MID1 interacting protein 1 |
| MYL9 | myosin, light chain 9, regulatory |
| MYRF | myelin regulatory factor |
| NPR1 | natriuretic peptide receptor 1 |
| NXN | nucleoredoxin |
| PALLD | palladin, cytoskeletal associated protein |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PDLIM1 | PDZ and LIM domain 1 |
| PIR | pirin (iron-binding nuclear protein) |
| PROM1 | prominin 1 |
| PSCA | prostate stem cell antigen |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| TPM1 | tropomyosin 1 (alpha) |
| TPM2 | tropomyosin 2 (beta) |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| Symbol | Name |
|---|---|
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| C4BPA | complement component 4 binding protein, alpha |
| CCND1 | cyclin D1 |
| CD44 | CD44 molecule (Indian blood group) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CIT | citron rho-interacting serine/threonine kinase |
| CPB1 | carboxypeptidase B1 (tissue) |
| CRLF1 | cytokine receptor-like factor 1 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) |
| EPHA3 | EPH receptor A3 |
| ETV1 | ets variant 1 |
| FAM129A | family with sequence similarity 129, member A |
| FZD1 | frizzled class receptor 1 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| MALL | mal, T-cell differentiation protein-like |
| MGLL | monoglyceride lipase |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MMP1 | matrix metallopeptidase 1 |
| MMP9 | matrix metallopeptidase 9 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PLAT | plasminogen activator, tissue |
| PLAUR | plasminogen activator, urokinase receptor |
| RAD51C | RAD51 paralog C |
| RGS13 | regulator of G-protein signaling 13 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| STC1 | stanniocalcin 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
