| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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118 genes differentially expressed following the BRD-K57169635_dacomitinib_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AGR2 | anterior gradient 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANXA4 | annexin A4 |
| APOD | apolipoprotein D |
| BAD | BCL2-associated agonist of cell death |
| BST2 | bone marrow stromal cell antigen 2 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCDC92 | coiled-coil domain containing 92 |
| CD9 | CD9 molecule |
| CLDN10 | claudin 10 |
| CP | ceruloplasmin (ferroxidase) |
| CTSB | cathepsin B |
| CTSD | cathepsin D |
| DEFB1 | defensin, beta 1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ESR1 | estrogen receptor 1 |
| FBLN1 | fibulin 1 |
| FGB | fibrinogen beta chain |
| FGFR4 | fibroblast growth factor receptor 4 |
| FMO3 | flavin containing monooxygenase 3 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX2 | glutathione peroxidase 2 |
| HBB | hemoglobin, beta |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMOX1 | heme oxygenase 1 |
| HOXB2 | homeobox B2 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LRRC16A | leucine rich repeat containing 16A |
| LY75 | lymphocyte antigen 75 |
| MEIS1 | Meis homeobox 1 |
| MMP12 | matrix metallopeptidase 12 |
| MOK | MOK protein kinase |
| MUC1 | mucin 1, cell surface associated |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OPTN | optineurin |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PERP | PERP, TP53 apoptosis effector |
| PLA2G16 | phospholipase A2, group XVI |
| PLCB4 | phospholipase C, beta 4 |
| PLIN2 | perilipin 2 |
| PSAP | prosaposin |
| QPRT | quinolinate phosphoribosyltransferase |
| RAB25 | RAB25, member RAS oncogene family |
| S100P | S100 calcium binding protein P |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| STC2 | stanniocalcin 2 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYT1 | synaptotagmin I |
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) |
| THAP11 | THAP domain containing 11 |
| TKT | transketolase |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNNC1 | troponin C type 1 (slow) |
| TPP1 | tripeptidyl peptidase I |
| TTC39A | tetratricopeptide repeat domain 39A |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| UGDH | UDP-glucose 6-dehydrogenase |
| VAT1 | vesicle amine transport 1 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARL4C | ADP-ribosylation factor-like 4C |
| CALR | calreticulin |
| CDC42 | cell division cycle 42 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| COL13A1 | collagen, type XIII, alpha 1 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 |
| DST | dystonin |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ETV5 | ets variant 5 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FST | follistatin |
| HBEGF | heparin-binding EGF-like growth factor |
| HES1 | hes family bHLH transcription factor 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| IER3 | immediate early response 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| INHBA | inhibin, beta A |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM6 | minichromosome maintenance complex component 6 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MYCBP | MYC binding protein |
| NFIB | nuclear factor I/B |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| P3H2 | prolyl 3-hydroxylase 2 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLAT | plasminogen activator, tissue |
| PTHLH | parathyroid hormone-like hormone |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAD51C | RAD51 paralog C |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| STC1 | stanniocalcin 1 |
| TGFB1 | transforming growth factor, beta 1 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
