| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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170 genes differentially expressed following the BRD-K57282030_JW-7-24-1_HS578T_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ANKRD36B | ankyrin repeat domain 36B |
| AREG | amphiregulin |
| ASPN | asporin |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC25B | cell division cycle 25B |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDK19 | cyclin-dependent kinase 19 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHGB | chromogranin B |
| CLEC2B | C-type lectin domain family 2, member B |
| COL10A1 | collagen, type X, alpha 1 |
| COL11A1 | collagen, type XI, alpha 1 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTGF | connective tissue growth factor |
| CXADR | coxsackie virus and adenovirus receptor |
| DCN | decorin |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| EMP1 | epithelial membrane protein 1 |
| EPAS1 | endothelial PAS domain protein 1 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FZD5 | frizzled class receptor 5 |
| GNLY | granulysin |
| GSE1 | Gse1 coiled-coil protein |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
| IGHM | immunoglobulin heavy constant mu |
| IRS2 | insulin receptor substrate 2 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| JAG1 | jagged 1 |
| KIZ | kizuna centrosomal protein |
| KRT18 | keratin 18, type I |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LOC100272216 | uncharacterized LOC100272216 |
| LUM | lumican |
| LXN | latexin |
| MAGEA3 | melanoma antigen family A3 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| NOX4 | NADPH oxidase 4 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NTS | neurotensin |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PDE9A | phosphodiesterase 9A |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB31 | RAB31, member RAS oncogene family |
| RBP1 | retinol binding protein 1, cellular |
| REG1A | regenerating islet-derived 1 alpha |
| RNASE6 | ribonuclease, RNase A family, k6 |
| RNF144A | ring finger protein 144A |
| S100A8 | S100 calcium binding protein A8 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STAR | steroidogenic acute regulatory protein |
| STON1 | stonin 1 |
| SULF1 | sulfatase 1 |
| SYT1 | synaptotagmin I |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TPP1 | tripeptidyl peptidase I |
| TRIB2 | tribbles pseudokinase 2 |
| TRIM2 | tripartite motif containing 2 |
| TSPAN7 | tetraspanin 7 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| VCAN | versican |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF277 | zinc finger protein 277 |
| Symbol | Name |
|---|---|
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ANXA6 | annexin A6 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| ATF5 | activating transcription factor 5 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| CALML5 | calmodulin-like 5 |
| CCNE2 | cyclin E2 |
| CCNF | cyclin F |
| CDC25A | cell division cycle 25A |
| CDC42 | cell division cycle 42 |
| CDC6 | cell division cycle 6 |
| CDK1 | cyclin-dependent kinase 1 |
| CDK2 | cyclin-dependent kinase 2 |
| CENPU | centromere protein U |
| CEP55 | centrosomal protein 55kDa |
| CLU | clusterin |
| COL9A3 | collagen, type IX, alpha 3 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DONSON | downstream neighbor of SON |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENO1 | enolase 1, (alpha) |
| EXO1 | exonuclease 1 |
| FANCI | Fanconi anemia, complementation group I |
| FEN1 | flap structure-specific endonuclease 1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GTSE1 | G-2 and S-phase expressed 1 |
| HAT1 | histone acetyltransferase 1 |
| HELLS | helicase, lymphoid-specific |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| KIF20A | kinesin family member 20A |
| KRT7 | keratin 7, type II |
| LIG1 | ligase I, DNA, ATP-dependent |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAP7 | microtubule-associated protein 7 |
| MATN2 | matrilin 2 |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM5 | minichromosome maintenance complex component 5 |
| MELK | maternal embryonic leucine zipper kinase |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYCBP | MYC binding protein |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NCAPG | non-SMC condensin I complex, subunit G |
| NET1 | neuroepithelial cell transforming 1 |
| NUP107 | nucleoporin 107kDa |
| NUP62 | nucleoporin 62kDa |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PBK | PDZ binding kinase |
| PCNA | proliferating cell nuclear antigen |
| PHGDH | phosphoglycerate dehydrogenase |
| PITX1 | paired-like homeodomain 1 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PRC1 | protein regulator of cytokinesis 1 |
| PRPF4 | pre-mRNA processing factor 4 |
| PSMC3IP | PSMC3 interacting protein |
| RAD51 | RAD51 recombinase |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RNASEH2A | ribonuclease H2, subunit A |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SMC2 | structural maintenance of chromosomes 2 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPP1 | secreted phosphoprotein 1 |
| SRM | spermidine synthase |
| STMN1 | stathmin 1 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TAGLN2 | transgelin 2 |
| TIMELESS | timeless circadian clock |
| TMEM194A | transmembrane protein 194A |
| TNC | tenascin C |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TYMS | thymidylate synthetase |
| ZWILCH | zwilch kinetochore protein |
| ZWINT | ZW10 interacting kinetochore protein |
