BRD-K57282030_JW-7-24-1_MCF7_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K57282030_JW-7-24-1_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGTR1 angiotensin II receptor, type 1
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANGPT1 angiopoietin 1
ASPH aspartate beta-hydroxylase
BICC1 BicC family RNA binding protein 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF10 chromosome 10 open reading frame 10
C1R complement component 1, r subcomponent
CD163 CD163 molecule
CHN1 chimerin 1
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
CP ceruloplasmin (ferroxidase)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTSZ cathepsin Z
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLK1 delta-like 1 homolog (Drosophila)
EGR1 early growth response 1
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
GDF15 growth differentiation factor 15
GLUL glutamate-ammonia ligase
GPM6B glycoprotein M6B
HBP1 HMG-box transcription factor 1
HSPA2 heat shock 70kDa protein 2
IRS2 insulin receptor substrate 2
KCTD12 potassium channel tetramerization domain containing 12
KDM5D lysine (K)-specific demethylase 5D
KIF20A kinesin family member 20A
KLF9 Kruppel-like factor 9
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MMD monocyte to macrophage differentiation-associated
MT1M metallothionein 1M
MTSS1 metastasis suppressor 1
NPTX2 neuronal pentraxin II
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRIP1 nuclear receptor interacting protein 1
PCOLCE procollagen C-endopeptidase enhancer
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG10 paternally expressed 10
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSD3 pleckstrin and Sec7 domain containing 3
PTN pleiotrophin
RGCC regulator of cell cycle
RHOBTB3 Rho-related BTB domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SNAI2 snail family zinc finger 2
SOD2 superoxide dismutase 2, mitochondrial
ST18 suppression of tumorigenicity 18, zinc finger
TBX3 T-box 3
TF transferrin
THBS2 thrombospondin 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
CAPG capping protein (actin filament), gelsolin-like
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLTB clathrin, light chain B
CLU clusterin
HOPX HOP homeobox
HSPB8 heat shock 22kDa protein 8
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
JCHAIN joining chain of multimeric IgA and IgM
KRT7 keratin 7, type II
PCP4 Purkinje cell protein 4
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLAC8 placenta-specific 8
S100A10 S100 calcium binding protein A10
SNAP25 synaptosomal-associated protein, 25kDa
TES testin LIM domain protein
TYRP1 tyrosinase-related protein 1
XIST X inactive specific transcript (non-protein coding)
Funding