BRD-K57592392_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K57592392_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BASP1 brain abundant, membrane attached signal protein 1
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CFD complement factor D (adipsin)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLU clusterin
COL4A2 collagen, type IV, alpha 2
CST3 cystatin C
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
DUSP5 dual specificity phosphatase 5
HOXC10 homeobox C10
HOXC6 homeobox C6
IGFBP4 insulin-like growth factor binding protein 4
JAG1 jagged 1
MAP1B microtubule-associated protein 1B
MARCKS myristoylated alanine-rich protein kinase C substrate
NAV3 neuron navigator 3
NEFL neurofilament, light polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
SPAG4 sperm associated antigen 4
STC1 stanniocalcin 1
VWF von Willebrand factor

decreased expression

Symbol Name
CD200 CD200 molecule
CD47 CD47 molecule
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DPP4 dipeptidyl-peptidase 4
EXT1 exostosin glycosyltransferase 1
FRZB frizzled-related protein
GREM1 gremlin 1, DAN family BMP antagonist
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IL17RB interleukin 17 receptor B
MMP7 matrix metallopeptidase 7
MRPL13 mitochondrial ribosomal protein L13
NMU neuromedin U
OLFM4 olfactomedin 4
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SDC2 syndecan 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPON1 spondin 1, extracellular matrix protein
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TSPAN7 tetraspanin 7