BRD-K57678861_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

51 genes differentially expressed following the BRD-K57678861_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
COBL cordon-bleu WH2 repeat protein
COL9A2 collagen, type IX, alpha 2
DDR1 discoidin domain receptor tyrosine kinase 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
LGALS1 lectin, galactoside-binding, soluble, 1
LOXL2 lysyl oxidase-like 2
MBNL1 muscleblind-like splicing regulator 1
NEFH neurofilament, heavy polypeptide
POSTN periostin, osteoblast specific factor
PRAME preferentially expressed antigen in melanoma
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP3 aquaporin 3 (Gill blood group)
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCND1 cyclin D1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
FGFBP1 fibroblast growth factor binding protein 1
GLUL glutamate-ammonia ligase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGHM immunoglobulin heavy constant mu
KRT13 keratin 13, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
MAT2A methionine adenosyltransferase II, alpha
MT1X metallothionein 1X
PI3 peptidase inhibitor 3, skin-derived
PITX1 paired-like homeodomain 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SATB1 SATB homeobox 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLPI secretory leukocyte peptidase inhibitor
SPRR1B small proline-rich protein 1B
SPRR3 small proline-rich protein 3
TGFBR3 transforming growth factor, beta receptor III
TRIM29 tripartite motif containing 29