BRD-K57732441_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K57732441_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD3 abhydrolase domain containing 3
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BGN biglycan
BLNK B-cell linker
C3ORF14 chromosome 3 open reading frame 14
CA2 carbonic anhydrase II
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCND2 cyclin D2
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CFD complement factor D (adipsin)
COL11A1 collagen, type XI, alpha 1
CTGF connective tissue growth factor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EIF5A eukaryotic translation initiation factor 5A
FGFR2 fibroblast growth factor receptor 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
LTB lymphotoxin beta (TNF superfamily, member 3)
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
MTSS1 metastasis suppressor 1
NARFL nuclear prelamin A recognition factor-like
NCF2 neutrophil cytosolic factor 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PID1 phosphotyrosine interaction domain containing 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB21 RAB21, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGCC regulator of cell cycle
S100A8 S100 calcium binding protein A8
SERINC5 serine incorporator 5
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SPON1 spondin 1, extracellular matrix protein
SQRDL sulfide quinone reductase-like (yeast)
SRGN serglycin
TOB1 transducer of ERBB2, 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WSB2 WD repeat and SOCS box containing 2

decreased expression

Symbol Name
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
DSP desmoplakin
EGR3 early growth response 3
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENDOD1 endonuclease domain containing 1
FAM57A family with sequence similarity 57, member A
GOLM1 golgi membrane protein 1
HNMT histamine N-methyltransferase
LGALS1 lectin, galactoside-binding, soluble, 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEIS1 Meis homeobox 1
MUC1 mucin 1, cell surface associated
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NFE2L2 nuclear factor, erythroid 2-like 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
PLAGL1 pleiomorphic adenoma gene-like 1
POSTN periostin, osteoblast specific factor
PRDX4 peroxiredoxin 4
PRMT1 protein arginine methyltransferase 1
PSRC1 proline/serine-rich coiled-coil 1
RAB38 RAB38, member RAS oncogene family
RHOBTB3 Rho-related BTB domain containing 3
SATB1 SATB homeobox 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPX sushi-repeat containing protein, X-linked
TACSTD2 tumor-associated calcium signal transducer 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
Funding