BRD-K58938839_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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51 genes differentially expressed following the BRD-K58938839_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ARID5B AT rich interactive domain 5B (MRF1-like)
C3 complement component 3
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLIC4 chloride intracellular channel 4
EGFR epidermal growth factor receptor
FGFBP1 fibroblast growth factor binding protein 1
GAS1 growth arrest-specific 1
GCLC glutamate-cysteine ligase, catalytic subunit
GSAP gamma-secretase activating protein
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IER2 immediate early response 2
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
INHBA inhibin, beta A
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
LAMC2 laminin, gamma 2
MAP7 microtubule-associated protein 7
PDLIM5 PDZ and LIM domain 5
PXDN peroxidasin
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFN stratifin
SLPI secretory leukocyte peptidase inhibitor
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
VSNL1 visinin-like 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CA2 carbonic anhydrase II
EVI2A ecotropic viral integration site 2A
FAM107A family with sequence similarity 107, member A
FGG fibrinogen gamma chain
G0S2 G0/G1 switch 2
GREB1 growth regulation by estrogen in breast cancer 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
LRRC41 leucine rich repeat containing 41
PAEP progestagen-associated endometrial protein
PLIN2 perilipin 2
PROM1 prominin 1
PTN pleiotrophin
SRGN serglycin
SRPX sushi-repeat containing protein, X-linked
THBD thrombomodulin
ZNF423 zinc finger protein 423