Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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169 genes differentially expressed following the BRD-K59317601_INK-128_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADGRF5 | adhesion G protein-coupled receptor F5 |
ANXA5 | annexin A5 |
APOD | apolipoprotein D |
ARHGAP29 | Rho GTPase activating protein 29 |
ASPN | asporin |
C10ORF10 | chromosome 10 open reading frame 10 |
CAPN2 | calpain 2, (m/II) large subunit |
CFH | complement factor H |
CLEC2B | C-type lectin domain family 2, member B |
CP | ceruloplasmin (ferroxidase) |
CST1 | cystatin SN |
CST4 | cystatin S |
CTGF | connective tissue growth factor |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DCN | decorin |
DUSP6 | dual specificity phosphatase 6 |
EGR1 | early growth response 1 |
EGR3 | early growth response 3 |
EPHA3 | EPH receptor A3 |
ETV1 | ets variant 1 |
FGFR1 | fibroblast growth factor receptor 1 |
FHL2 | four and a half LIM domains 2 |
FILIP1L | filamin A interacting protein 1-like |
GLRX | glutaredoxin (thioltransferase) |
GOLM1 | golgi membrane protein 1 |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HOXB6 | homeobox B6 |
ICAM1 | intercellular adhesion molecule 1 |
IDS | iduronate 2-sulfatase |
IER2 | immediate early response 2 |
IER3 | immediate early response 3 |
IFI16 | interferon, gamma-inducible protein 16 |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
IGFBP1 | insulin-like growth factor binding protein 1 |
IL6ST | interleukin 6 signal transducer |
INPP1 | inositol polyphosphate-1-phosphatase |
ITGB5 | integrin, beta 5 |
KRT18 | keratin 18, type I |
LEF1 | lymphoid enhancer-binding factor 1 |
LPP | LIM domain containing preferred translocation partner in lipoma |
LRP10 | low density lipoprotein receptor-related protein 10 |
LXN | latexin |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MT2A | metallothionein 2A |
MTUS1 | microtubule associated tumor suppressor 1 |
MVP | major vault protein |
MYO6 | myosin VI |
MYOF | myoferlin |
NAV2 | neuron navigator 2 |
NNMT | nicotinamide N-methyltransferase |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
NT5E | 5'-nucleotidase, ecto (CD73) |
PDLIM5 | PDZ and LIM domain 5 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PLA2G16 | phospholipase A2, group XVI |
PLS3 | plastin 3 |
PPAP2C | phosphatidic acid phosphatase type 2C |
PROS1 | protein S (alpha) |
RND3 | Rho family GTPase 3 |
RPS27L | ribosomal protein S27-like |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
SLC22A18 | solute carrier family 22, member 18 |
SOX9 | SRY (sex determining region Y)-box 9 |
SPRY2 | sprouty homolog 2 (Drosophila) |
SQSTM1 | sequestosome 1 |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TGM2 | transglutaminase 2 |
THBS1 | thrombospondin 1 |
TM4SF1 | transmembrane 4 L six family member 1 |
TM9SF3 | transmembrane 9 superfamily member 3 |
TPM1 | tropomyosin 1 (alpha) |
TSPAN4 | tetraspanin 4 |
TXNIP | thioredoxin interacting protein |
VCL | vinculin |
ZBTB16 | zinc finger and BTB domain containing 16 |
ZMYND8 | zinc finger, MYND-type containing 8 |
Symbol | Name |
---|---|
ACTA1 | actin, alpha 1, skeletal muscle |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
ALOX5 | arachidonate 5-lipoxygenase |
AQP3 | aquaporin 3 (Gill blood group) |
ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
BIRC5 | baculoviral IAP repeat containing 5 |
CA12 | carbonic anhydrase XII |
CA2 | carbonic anhydrase II |
CCNA2 | cyclin A2 |
CCNE1 | cyclin E1 |
CDK1 | cyclin-dependent kinase 1 |
CKAP4 | cytoskeleton-associated protein 4 |
CLCA2 | chloride channel accessory 2 |
CLIC3 | chloride intracellular channel 3 |
CRYAB | crystallin, alpha B |
CSTA | cystatin A (stefin A) |
DACH1 | dachshund family transcription factor 1 |
DAPK1 | death-associated protein kinase 1 |
ELP5 | elongator acetyltransferase complex subunit 5 |
FABP7 | fatty acid binding protein 7, brain |
FBN2 | fibrillin 2 |
FGFBP1 | fibroblast growth factor binding protein 1 |
FHL1 | four and a half LIM domains 1 |
GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
GINS1 | GINS complex subunit 1 (Psf1 homolog) |
GINS2 | GINS complex subunit 2 (Psf2 homolog) |
GPI | glucose-6-phosphate isomerase |
GPM6B | glycoprotein M6B |
GRWD1 | glutamate-rich WD repeat containing 1 |
HBB | hemoglobin, beta |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HMOX1 | heme oxygenase 1 |
IGKC | immunoglobulin kappa constant |
IGL | immunoglobulin lambda locus |
IL1RN | interleukin 1 receptor antagonist |
IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
KRT13 | keratin 13, type I |
KRT16 | keratin 16, type I |
KRT17 | keratin 17, type I |
KRT4 | keratin 4, type II |
KRT5 | keratin 5, type II |
KRT6A | keratin 6A, type II |
KRT6B | keratin 6B, type II |
LTF | lactotransferrin |
LYZ | lysozyme |
MAL | mal, T-cell differentiation protein |
MB | myoglobin |
MCAM | melanoma cell adhesion molecule |
MREG | melanoregulin |
NEB | nebulin |
NEBL | nebulette |
OPN3 | opsin 3 |
P3H2 | prolyl 3-hydroxylase 2 |
PHGDH | phosphoglycerate dehydrogenase |
PI3 | peptidase inhibitor 3, skin-derived |
PKP1 | plakophilin 1 |
POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
RAD51C | RAD51 paralog C |
RYR1 | ryanodine receptor 1 (skeletal) |
S100A7 | S100 calcium binding protein A7 |
S100A8 | S100 calcium binding protein A8 |
S100A9 | S100 calcium binding protein A9 |
S100P | S100 calcium binding protein P |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
SLN | sarcolipin |
SLPI | secretory leukocyte peptidase inhibitor |
SPRR1A | small proline-rich protein 1A |
SPRR1B | small proline-rich protein 1B |
SPRR2B | small proline-rich protein 2B |
SPRR3 | small proline-rich protein 3 |
TNIP1 | TNFAIP3 interacting protein 1 |
TNNT1 | troponin T type 1 (skeletal, slow) |
TRIM16 | tripartite motif containing 16 |
TRIP13 | thyroid hormone receptor interactor 13 |
TSPYL5 | TSPY-like 5 |
TTN | titin |
TYROBP | TYRO protein tyrosine kinase binding protein |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
VCAM1 | vascular cell adhesion molecule 1 |
WASF1 | WAS protein family, member 1 |
WNT5A | wingless-type MMTV integration site family, member 5A |