BRD-K59369769_HY-10161_HT29_6.0_h_10.0_um Gene Set
Genes
58 genes differentially expressed following the BRD-K59369769_HY-10161_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ADIPOQ
|
adiponectin, C1Q and collagen domain containing
|
|
AKR1C3
|
aldo-keto reductase family 1, member C3
|
|
ASPM
|
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
|
|
ATHL1
|
ATH1, acid trehalase-like 1 (yeast)
|
|
AURKA
|
aurora kinase A
|
|
CCNG2
|
cyclin G2
|
|
CFD
|
complement factor D (adipsin)
|
|
DLGAP5
|
discs, large (Drosophila) homolog-associated protein 5
|
|
EFNA1
|
ephrin-A1
|
|
ERBB3
|
erb-b2 receptor tyrosine kinase 3
|
|
FOXO4
|
forkhead box O4
|
|
HBP1
|
HMG-box transcription factor 1
|
|
HMGB3
|
high mobility group box 3
|
|
INSIG1
|
insulin induced gene 1
|
|
JUP
|
junction plakoglobin
|
|
KLHDC2
|
kelch domain containing 2
|
|
MYO6
|
myosin VI
|
|
NDC80
|
NDC80 kinetochore complex component
|
|
NQO1
|
NAD(P)H dehydrogenase, quinone 1
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
|
RNASE1
|
ribonuclease, RNase A family, 1 (pancreatic)
|
|
SCNN1A
|
sodium channel, non voltage gated 1 alpha subunit
|
|
SH3BGRL
|
SH3 domain binding glutamate-rich protein like
|
|
TBL1X
|
transducin (beta)-like 1X-linked
|
|
TPSAB1
|
tryptase alpha/beta 1
|
|
TPSB2
|
tryptase beta 2 (gene/pseudogene)
|
|
TTK
|
TTK protein kinase
|
|
TUBA1A
|
tubulin, alpha 1a
|
decreased expression
| Symbol |
Name |
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide
|
|
CDC25A
|
cell division cycle 25A
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
|
DDX21
|
DEAD (Asp-Glu-Ala-Asp) box helicase 21
|
|
DPH2
|
DPH2 homolog (S. cerevisiae)
|
|
DUSP6
|
dual specificity phosphatase 6
|
|
EGR2
|
early growth response 2
|
|
EGR3
|
early growth response 3
|
|
FHL2
|
four and a half LIM domains 2
|
|
FOSL1
|
FOS-like antigen 1
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
|
HOMER1
|
homer scaffolding protein 1
|
|
IER3
|
immediate early response 3
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
|
LIF
|
leukemia inhibitory factor
|
|
MAP2K3
|
mitogen-activated protein kinase kinase 3
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
|
NOLC1
|
nucleolar and coiled-body phosphoprotein 1
|
|
NXT1
|
nuclear transport factor 2-like export factor 1
|
|
PEG3
|
paternally expressed 3
|
|
PHLDA1
|
pleckstrin homology-like domain, family A, member 1
|
|
PNO1
|
partner of NOB1 homolog (S. cerevisiae)
|
|
PNP
|
purine nucleoside phosphorylase
|
|
PPRC1
|
peroxisome proliferator-activated receptor gamma, coactivator-related 1
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
|
RGS2
|
regulator of G-protein signaling 2
|
|
SLC20A1
|
solute carrier family 20 (phosphate transporter), member 1
|
|
SPRY2
|
sprouty homolog 2 (Drosophila)
|
|
SRM
|
spermidine synthase
|
