Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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102 genes differentially expressed following the BRD-K59456551_l-glutamic acid, n-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- [cas]_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
AFF1 | AF4/FMR2 family, member 1 |
AGR2 | anterior gradient 2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
BSG | basigin (Ok blood group) |
BST2 | bone marrow stromal cell antigen 2 |
C6ORF48 | chromosome 6 open reading frame 48 |
CERS6 | ceramide synthase 6 |
COCH | cochlin |
CST3 | cystatin C |
DAPK1 | death-associated protein kinase 1 |
DDB2 | damage-specific DNA binding protein 2, 48kDa |
DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
DSP | desmoplakin |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
FCGBP | Fc fragment of IgG binding protein |
FGB | fibrinogen beta chain |
GPX2 | glutathione peroxidase 2 |
IGFBP6 | insulin-like growth factor binding protein 6 |
IQGAP2 | IQ motif containing GTPase activating protein 2 |
KAT6B | K(lysine) acetyltransferase 6B |
KLF9 | Kruppel-like factor 9 |
LGALS4 | lectin, galactoside-binding, soluble, 4 |
LTBP3 | latent transforming growth factor beta binding protein 3 |
MAP1B | microtubule-associated protein 1B |
PDGFA | platelet-derived growth factor alpha polypeptide |
PFKL | phosphofructokinase, liver |
S100A7 | S100 calcium binding protein A7 |
SDC4 | syndecan 4 |
SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
SPEN | spen family transcriptional repressor |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
SRGN | serglycin |
SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
TFF1 | trefoil factor 1 |
TJP2 | tight junction protein 2 |
TKTL1 | transketolase-like 1 |
TM4SF4 | transmembrane 4 L six family member 4 |
TSPAN8 | tetraspanin 8 |
TST | thiosulfate sulfurtransferase (rhodanese) |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
XPO7 | exportin 7 |
ZIC1 | Zic family member 1 |
Symbol | Name |
---|---|
AHR | aryl hydrocarbon receptor |
AMD1 | adenosylmethionine decarboxylase 1 |
BCL6 | B-cell CLL/lymphoma 6 |
CAMP | cathelicidin antimicrobial peptide |
CD24 | CD24 molecule |
CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
CLIC4 | chloride intracellular channel 4 |
CPE | carboxypeptidase E |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
DPYSL3 | dihydropyrimidinase-like 3 |
EDNRB | endothelin receptor type B |
EGFL6 | EGF-like-domain, multiple 6 |
EIF5 | eukaryotic translation initiation factor 5 |
EPYC | epiphycan |
ESRP1 | epithelial splicing regulatory protein 1 |
EVI2A | ecotropic viral integration site 2A |
GAL | galanin/GMAP prepropeptide |
HIST1H1C | histone cluster 1, H1c |
HIST1H2AE | histone cluster 1, H2ae |
HIST1H2BG | histone cluster 1, H2bg |
HSPA1A | heat shock 70kDa protein 1A |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IL1R1 | interleukin 1 receptor, type I |
KIF20A | kinesin family member 20A |
KLK11 | kallikrein-related peptidase 11 |
KRT23 | keratin 23, type I |
LMCD1 | LIM and cysteine-rich domains 1 |
LMO2 | LIM domain only 2 (rhombotin-like 1) |
LPAR6 | lysophosphatidic acid receptor 6 |
MAP7 | microtubule-associated protein 7 |
MFAP5 | microfibrillar associated protein 5 |
MMP10 | matrix metallopeptidase 10 |
MMP9 | matrix metallopeptidase 9 |
NCK1 | NCK adaptor protein 1 |
NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PSRC1 | proline/serine-rich coiled-coil 1 |
RGCC | regulator of cell cycle |
RPIA | ribose 5-phosphate isomerase A |
RTN2 | reticulon 2 |
SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SLC38A2 | solute carrier family 38, member 2 |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
SPON1 | spondin 1, extracellular matrix protein |
SST | somatostatin |
ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TNNT1 | troponin T type 1 (skeletal, slow) |