BRD-K59488055_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

20 genes differentially expressed following the BRD-K59488055_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDOB aldolase B, fructose-bisphosphate
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
DHCR7 7-dehydrocholesterol reductase
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PPAP2B phosphatidic acid phosphatase type 2B
PRSS8 protease, serine, 8
STC1 stanniocalcin 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
DAPK1 death-associated protein kinase 1
IGF1R insulin-like growth factor 1 receptor
TXNDC9 thioredoxin domain containing 9