BRD-K60219430_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

24 genes differentially expressed following the BRD-K60219430_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BIN1 bridging integrator 1
BLCAP bladder cancer associated protein
BLVRB biliverdin reductase B
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
CLIC4 chloride intracellular channel 4
CYB5R1 cytochrome b5 reductase 1
FADS1 fatty acid desaturase 1
INSIG1 insulin induced gene 1
MKRN1 makorin ring finger protein 1
MOCOS molybdenum cofactor sulfurase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
TBL1X transducin (beta)-like 1X-linked

decreased expression

Symbol Name
AURKA aurora kinase A
AURKB aurora kinase B
BEX1 brain expressed, X-linked 1
CCNB1 cyclin B1
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PROM1 prominin 1
TOP2A topoisomerase (DNA) II alpha 170kDa