BRD-K60219430_serdemetan_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

13 genes differentially expressed following the BRD-K60219430_serdemetan_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDB2 damage-specific DNA binding protein 2, 48kDa
FDXR ferredoxin reductase
GATA2 GATA binding protein 2
KRT13 keratin 13, type I
SESN1 sestrin 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF21 tumor necrosis factor receptor superfamily, member 21

decreased expression

Symbol Name
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
ENO1 enolase 1, (alpha)
IL1R1 interleukin 1 receptor, type I
LTF lactotransferrin
MMP9 matrix metallopeptidase 9
Funding