BRD-K60297835_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K60297835_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
APOD apolipoprotein D
ARG2 arginase 2
BASP1 brain abundant, membrane attached signal protein 1
CCNA1 cyclin A1
CD24 CD24 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COLEC12 collectin sub-family member 12
CRABP2 cellular retinoic acid binding protein 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXADR coxsackie virus and adenovirus receptor
DUSP10 dual specificity phosphatase 10
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
FBP1 fructose-1,6-bisphosphatase 1
FN1 fibronectin 1
GDF15 growth differentiation factor 15
IL1B interleukin 1, beta
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LDOC1 leucine zipper, down-regulated in cancer 1
LEF1 lymphoid enhancer-binding factor 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS4 lectin, galactoside-binding, soluble, 4
MMD monocyte to macrophage differentiation-associated
MYO1B myosin IB
NCF2 neutrophil cytosolic factor 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCA protein kinase C, alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
RGCC regulator of cell cycle
RGS10 regulator of G-protein signaling 10
RGS2 regulator of G-protein signaling 2
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
SDC4 syndecan 4
SMAD3 SMAD family member 3
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1
TSC22D1 TSC22 domain family, member 1
WEE1 WEE1 G2 checkpoint kinase

decreased expression

Symbol Name
CCND2 cyclin D2
CDV3 CDV3 homolog (mouse)
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
GPM6B glycoprotein M6B
LTF lactotransferrin
MAGEA6 melanoma antigen family A6
PLTP phospholipid transfer protein
PNN pinin, desmosome associated protein
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
TFF1 trefoil factor 1
VCAM1 vascular cell adhesion molecule 1