BRD-K60511616_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K60511616_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGR2 anterior gradient 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
CCNG2 cyclin G2
CSTA cystatin A (stefin A)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
FSTL1 follistatin-like 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
LDHB lactate dehydrogenase B
MATN2 matrilin 2
NID2 nidogen 2 (osteonidogen)
NPY1R neuropeptide Y receptor Y1
NTS neurotensin
OLFM4 olfactomedin 4
PLA2G16 phospholipase A2, group XVI
PLCB4 phospholipase C, beta 4
QPCT glutaminyl-peptide cyclotransferase
QSOX1 quiescin Q6 sulfhydryl oxidase 1
S100P S100 calcium binding protein P
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
TSPAN8 tetraspanin 8
VIM vimentin
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ATAD2 ATPase family, AAA domain containing 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BHLHE41 basic helix-loop-helix family, member e41
DHRS3 dehydrogenase/reductase (SDR family) member 3
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENO1 enolase 1, (alpha)
IFRD2 interferon-related developmental regulator 2
LARP1 La ribonucleoprotein domain family, member 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
PLEC plectin
PODXL podocalyxin-like
POSTN periostin, osteoblast specific factor
RSL1D1 ribosomal L1 domain containing 1
S100A7 S100 calcium binding protein A7
SEPP1 selenoprotein P, plasma, 1
TAGLN2 transgelin 2
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TKT transketolase
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
YIPF5 Yip1 domain family, member 5