BRD-K60762818_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K60762818_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
BASP1 brain abundant, membrane attached signal protein 1
CST1 cystatin SN
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DSP desmoplakin
FDPS farnesyl diphosphate synthase
FOXO3 forkhead box O3
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP4 insulin-like growth factor binding protein 4
INSIG1 insulin induced gene 1
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
LPIN1 lipin 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
MYO6 myosin VI
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NSDHL NAD(P) dependent steroid dehydrogenase-like
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFRP4 secreted frizzled-related protein 4
SOX4 SRY (sex determining region Y)-box 4
SQLE squalene epoxidase
SQSTM1 sequestosome 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
CA2 carbonic anhydrase II
CRABP1 cellular retinoic acid binding protein 1
HSPB8 heat shock 22kDa protein 8
MN1 meningioma (disrupted in balanced translocation) 1
NPTX2 neuronal pentraxin II
SCUBE2 signal peptide, CUB domain, EGF-like 2
SRSF6 serine/arginine-rich splicing factor 6
STOM stomatin
ZIC1 Zic family member 1
Funding