BRD-K60895275_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K60895275_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANPEP alanyl (membrane) aminopeptidase
BCAM basal cell adhesion molecule (Lutheran blood group)
CXCL14 chemokine (C-X-C motif) ligand 14
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FGFR1 fibroblast growth factor receptor 1
FOLR1 folate receptor 1 (adult)
FTH1 ferritin, heavy polypeptide 1
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GCLM glutamate-cysteine ligase, modifier subunit
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
KYNU kynureninase
LDOC1 leucine zipper, down-regulated in cancer 1
LIMCH1 LIM and calponin homology domains 1
LOX lysyl oxidase
MCUR1 mitochondrial calcium uniporter regulator 1
MDFIC MyoD family inhibitor domain containing
NEBL nebulette
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIR pirin (iron-binding nuclear protein)
RGS1 regulator of G-protein signaling 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TGFBI transforming growth factor, beta-induced, 68kDa
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
GSTZ1 glutathione S-transferase zeta 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL13RA2 interleukin 13 receptor, alpha 2
MRPS16 mitochondrial ribosomal protein S16
NDP Norrie disease (pseudoglioma)
NPY1R neuropeptide Y receptor Y1
SRSF6 serine/arginine-rich splicing factor 6
TESC tescalcin
TNIP1 TNFAIP3 interacting protein 1
Funding