BRD-K62810658_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K62810658_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMOTL2 angiomotin like 2
CCND2 cyclin D2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFB complement factor B
RNF167 ring finger protein 167
S100A9 S100 calcium binding protein A9
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCND1 cyclin D1
CXCL8 chemokine (C-X-C motif) ligand 8
F2RL1 coagulation factor II (thrombin) receptor-like 1
GAL galanin/GMAP prepropeptide
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
IL1R1 interleukin 1 receptor, type I
PHLDA1 pleckstrin homology-like domain, family A, member 1
RGS2 regulator of G-protein signaling 2
STC1 stanniocalcin 1
STX1A syntaxin 1A (brain)
THBD thrombomodulin
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
UGDH UDP-glucose 6-dehydrogenase
VGLL4 vestigial-like family member 4