BRD-K62818989_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K62818989_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
COL1A2 collagen, type I, alpha 2
CRYAB crystallin, alpha B
DCN decorin
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EIF5A eukaryotic translation initiation factor 5A
FABP4 fatty acid binding protein 4, adipocyte
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IGHD immunoglobulin heavy constant delta
ISG15 ISG15 ubiquitin-like modifier
KRT18 keratin 18, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LAPTM5 lysosomal protein transmembrane 5
LOC100505650 uncharacterized LOC100505650
MCAM melanoma cell adhesion molecule
MGP matrix Gla protein
PLIN2 perilipin 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RGS2 regulator of G-protein signaling 2
SMAD3 SMAD family member 3
TM4SF1 transmembrane 4 L six family member 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARG1 arginase 1
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CXCL12 chemokine (C-X-C motif) ligand 12
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
MEIS2 Meis homeobox 2
PERP PERP, TP53 apoptosis effector
STK39 serine threonine kinase 39
TPBG trophoblast glycoprotein