BRD-K62970326_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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35 genes differentially expressed following the BRD-K62970326_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ASNS asparagine synthetase (glutamine-hydrolyzing)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DDIT4 DNA-damage-inducible transcript 4
DPYSL2 dihydropyrimidinase-like 2
ELANE elastase, neutrophil expressed
FSD1 fibronectin type III and SPRY domain containing 1
HIST1H2BG histone cluster 1, H2bg
INHBA inhibin, beta A
MYC v-myc avian myelocytomatosis viral oncogene homolog
PCP4 Purkinje cell protein 4
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
RHOBTB3 Rho-related BTB domain containing 3
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
SERINC5 serine incorporator 5
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TMX4 thioredoxin-related transmembrane protein 4
TRIB3 tribbles pseudokinase 3
VCAN versican
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
CFB complement factor B
COL6A2 collagen, type VI, alpha 2
FGFR3 fibroblast growth factor receptor 3
FXYD1 FXYD domain containing ion transport regulator 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
LUC7L3 LUC7-like 3 (S. cerevisiae)
MFAP4 microfibrillar-associated protein 4
RPS4Y1 ribosomal protein S4, Y-linked 1
TGFBR3 transforming growth factor, beta receptor III
TUBB6 tubulin, beta 6 class V
ZNF586 zinc finger protein 586