| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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133 genes differentially expressed following the BRD-K63068307_ZSTK-474_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AGR2 | anterior gradient 2 |
| AHNAK | AHNAK nucleoprotein |
| ANKRD10 | ankyrin repeat domain 10 |
| BEX4 | brain expressed, X-linked 4 |
| BTBD3 | BTB (POZ) domain containing 3 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CAMLG | calcium modulating ligand |
| CCDC92 | coiled-coil domain containing 92 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| COMP | cartilage oligomeric matrix protein |
| CTGF | connective tissue growth factor |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| DAPK1 | death-associated protein kinase 1 |
| DES | desmin |
| EPHA3 | EPH receptor A3 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FBN1 | fibrillin 1 |
| GAS6 | growth arrest-specific 6 |
| GOLGA8A | golgin A8 family, member A |
| GOLGA8B | golgin A8 family, member B |
| GOLGA8H | golgin A8 family, member H |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| GSDMB | gasdermin B |
| HDAC9 | histone deacetylase 9 |
| HEBP1 | heme binding protein 1 |
| HIST1H2BK | histone cluster 1, H2bk |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-E | major histocompatibility complex, class I, E |
| HMGA1 | high mobility group AT-hook 1 |
| HMGA2 | high mobility group AT-hook 2 |
| INHBA | inhibin, beta A |
| IPO7 | importin 7 |
| IRS2 | insulin receptor substrate 2 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LOC283683 | uncharacterized LOC283683 |
| LYZ | lysozyme |
| MANSC1 | MANSC domain containing 1 |
| MFAP5 | microfibrillar associated protein 5 |
| MPDZ | multiple PDZ domain protein |
| MVP | major vault protein |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRN1 | neuritin 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PERP | PERP, TP53 apoptosis effector |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P |
| PLXNC1 | plexin C1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| PYCARD | PYD and CARD domain containing |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RPL22 | ribosomal protein L22 |
| SATB1 | SATB homeobox 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| STC1 | stanniocalcin 1 |
| STX1A | syntaxin 1A (brain) |
| SVIL | supervillin |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TOX3 | TOX high mobility group box family member 3 |
| TPP1 | tripeptidyl peptidase I |
| ZNF277 | zinc finger protein 277 |
| Symbol | Name |
|---|---|
| AARS | alanyl-tRNA synthetase |
| ADM | adrenomedullin |
| AK4 | adenylate kinase 4 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| AURKA | aurora kinase A |
| CA12 | carbonic anhydrase XII |
| CCNA2 | cyclin A2 |
| CLU | clusterin |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTSZ | cathepsin Z |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| EBP | emopamil binding protein (sterol isomerase) |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ESR1 | estrogen receptor 1 |
| FEN1 | flap structure-specific endonuclease 1 |
| FOLR1 | folate receptor 1 (adult) |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GPC3 | glypican 3 |
| GPI | glucose-6-phosphate isomerase |
| HAT1 | histone acetyltransferase 1 |
| HSPA14 | heat shock 70kDa protein 14 |
| KRT15 | keratin 15, type I |
| KRT5 | keratin 5, type II |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LOC100505650 | uncharacterized LOC100505650 |
| LTF | lactotransferrin |
| LUM | lumican |
| MALL | mal, T-cell differentiation protein-like |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MREG | melanoregulin |
| MSMO1 | methylsterol monooxygenase 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| PCP4 | Purkinje cell protein 4 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRDX1 | peroxiredoxin 1 |
| PRR15L | proline rich 15-like |
| PTN | pleiotrophin |
| RAI14 | retinoic acid induced 14 |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RGS2 | regulator of G-protein signaling 2 |
| RIT1 | Ras-like without CAAX 1 |
| RRM2 | ribonucleotide reductase M2 |
| SFN | stratifin |
| SFTPA2 | surfactant protein A2 |
| SFTPB | surfactant protein B |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SUSD4 | sushi domain containing 4 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TBL1X | transducin (beta)-like 1X-linked |
| TF | transferrin |
| TOR3A | torsin family 3, member A |
| WFDC2 | WAP four-disulfide core domain 2 |
| WIF1 | WNT inhibitory factor 1 |
