BRD-K63072637_Pyrantel tartrate_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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51 genes differentially expressed following the BRD-K63072637_Pyrantel tartrate_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
CD59 CD59 molecule, complement regulatory protein
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CREM cAMP responsive element modulator
DPY19L1 dpy-19-like 1 (C. elegans)
EIF5A eukaryotic translation initiation factor 5A
GTPBP8 GTP-binding protein 8 (putative)
KIAA1033 KIAA1033
LPCAT1 lysophosphatidylcholine acyltransferase 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PALLD palladin, cytoskeletal associated protein
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLSCR1 phospholipid scramblase 1
QPCT glutaminyl-peptide cyclotransferase
RPS11 ribosomal protein S11
S100A10 S100 calcium binding protein A10
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TSPAN3 tetraspanin 3
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CLEC2B C-type lectin domain family 2, member B
COL15A1 collagen, type XV, alpha 1
COL6A1 collagen, type VI, alpha 1
CSTA cystatin A (stefin A)
CX3CR1 chemokine (C-X3-C motif) receptor 1
DPYSL3 dihydropyrimidinase-like 3
FAM129A family with sequence similarity 129, member A
FGL2 fibrinogen-like 2
GJA1 gap junction protein, alpha 1, 43kDa
JAG1 jagged 1
KLK10 kallikrein-related peptidase 10
LAMA4 laminin, alpha 4
MKNK1 MAP kinase interacting serine/threonine kinase 1
NID1 nidogen 1
NVL nuclear VCP-like
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG10 paternally expressed 10
RGCC regulator of cell cycle
SCUBE2 signal peptide, CUB domain, EGF-like 2
SPARCL1 SPARC-like 1 (hevin)
STAR steroidogenic acute regulatory protein
TPP1 tripeptidyl peptidase I
VTCN1 V-set domain containing T cell activation inhibitor 1