BRD-K63151507_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K63151507_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA6 annexin A6
ASCL1 achaete-scute family bHLH transcription factor 1
BCL6 B-cell CLL/lymphoma 6
FAM134B family with sequence similarity 134, member B
FTH1 ferritin, heavy polypeptide 1
HEBP1 heme binding protein 1
HMOX1 heme oxygenase 1
IRS2 insulin receptor substrate 2
OLFM1 olfactomedin 1
PVALB parvalbumin
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
CDC42 cell division cycle 42
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
DCK deoxycytidine kinase
EPHA3 EPH receptor A3
FLRT2 fibronectin leucine rich transmembrane protein 2
HEPH hephaestin
MGP matrix Gla protein
OLFM4 olfactomedin 4
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PMP22 peripheral myelin protein 22
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
SPP1 secreted phosphoprotein 1
TCF4 transcription factor 4
ZEB1 zinc finger E-box binding homeobox 1