BRD-K63550407_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K63550407_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
CPB1 carboxypeptidase B1 (tissue)
DACH1 dachshund family transcription factor 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
FBLN1 fibulin 1
GAGE3 G antigen 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IGKV4-1 immunoglobulin kappa variable 4-1
JCHAIN joining chain of multimeric IgA and IgM
LCN2 lipocalin 2
MMP7 matrix metallopeptidase 7
NPTX2 neuronal pentraxin II
NT5E 5'-nucleotidase, ecto (CD73)
OLFM4 olfactomedin 4
PLEKHA5 pleckstrin homology domain containing, family A member 5
PMP22 peripheral myelin protein 22
QPCT glutaminyl-peptide cyclotransferase
REG3A regenerating islet-derived 3 alpha
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
TFPI2 tissue factor pathway inhibitor 2

decreased expression

Symbol Name
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
CD59 CD59 molecule, complement regulatory protein
CRYAB crystallin, alpha B
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENO1 enolase 1, (alpha)
FABP7 fatty acid binding protein 7, brain
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
LAMA4 laminin, alpha 4
PDLIM5 PDZ and LIM domain 5
PRMT1 protein arginine methyltransferase 1
RSL1D1 ribosomal L1 domain containing 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRSF6 serine/arginine-rich splicing factor 6
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TKT transketolase
TPM4 tropomyosin 4
UBE2S ubiquitin-conjugating enzyme E2S