| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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118 genes differentially expressed following the BRD-K64052750_gefitinib_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACKR3 | atypical chemokine receptor 3 |
| ADCK3 | aarF domain containing kinase 3 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CLDN3 | claudin 3 |
| COPA | coatomer protein complex, subunit alpha |
| CSF1R | colony stimulating factor 1 receptor |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DUSP6 | dual specificity phosphatase 6 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FHL1 | four and a half LIM domains 1 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GSN | gelsolin |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 |
| JADE2 | jade family PHD finger 2 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| MECOM | MDS1 and EVI1 complex locus |
| MFAP5 | microfibrillar associated protein 5 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A |
| MSLN | mesothelin |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MVP | major vault protein |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| MYO1D | myosin ID |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| ODAM | odontogenic, ameloblast asssociated |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLTP | phospholipid transfer protein |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RAB40B | RAB40B, member RAS oncogene family |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS1 | regulator of G-protein signaling 1 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| SCARB2 | scavenger receptor class B, member 2 |
| SDC4 | syndecan 4 |
| SESN1 | sestrin 1 |
| TF | transferrin |
| TLE2 | transducin-like enhancer of split 2 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TXNIP | thioredoxin interacting protein |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) |
| ZNF652 | zinc finger protein 652 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| ANXA1 | annexin A1 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| AURKA | aurora kinase A |
| BTG3 | BTG family, member 3 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNA2 | cyclin A2 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CDCA3 | cell division cycle associated 3 |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPF | centromere protein F, 350/400kDa |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DEPDC1 | DEP domain containing 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| E2F2 | E2F transcription factor 2 |
| EGR2 | early growth response 2 |
| FABP7 | fatty acid binding protein 7, brain |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GLIPR1 | GLI pathogenesis-related 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HMGB2 | high mobility group box 2 |
| JAG1 | jagged 1 |
| KIF20A | kinesin family member 20A |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| KRT81 | keratin 81, type II |
| KYNU | kynureninase |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MELK | maternal embryonic leucine zipper kinase |
| NEK2 | NIMA-related kinase 2 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| ODC1 | ornithine decarboxylase 1 |
| PCP4 | Purkinje cell protein 4 |
| PDLIM5 | PDZ and LIM domain 5 |
| PLK1 | polo-like kinase 1 |
| PRC1 | protein regulator of cytokinesis 1 |
| PTTG1 | pituitary tumor-transforming 1 |
| RRM2 | ribonucleotide reductase M2 |
| S100A7 | S100 calcium binding protein A7 |
| SEC61G | Sec61 gamma subunit |
| SLPI | secretory leukocyte peptidase inhibitor |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TNC | tenascin C |
| TRIB2 | tribbles pseudokinase 2 |
| TUBB4B | tubulin, beta 4B class IVb |
| TUSC3 | tumor suppressor candidate 3 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
